Neuropathogenesis of congenital cytomegalovirus infection: disease mechanisms and prospects for intervention
MCJ Cheeran, JR Lokensgard… - Clinical microbiology …, 2009 - Am Soc Microbiol
Congenital cytomegalovirus (CMV) infection is the leading infectious cause of mental
retardation and hearing loss in the developed world. In recent years, there has been an …
retardation and hearing loss in the developed world. In recent years, there has been an …
Cytomegalovirus infection and inflammation in developing brain
Human cytomegalovirus (HCMV) is a highly prevalent herpesvirus that can cause severe
disease in immunocompromised individuals and immunologically immature fetuses and …
disease in immunocompromised individuals and immunologically immature fetuses and …
Role of nitric oxide produced by iNOS through NF-κB pathway in migration of cerebellar granule neurons induced by Lipopolysaccharide
D Arias-Salvatierra, EK Silbergeld… - Cellular signalling, 2011 - Elsevier
Inflammatory stimulus during development increases the risk for adverse neurologic
outcome. One possible mechanism is disrupting neuronal migration. Using …
outcome. One possible mechanism is disrupting neuronal migration. Using …
[HTML][HTML] A congenital CMV infection model for follow-up studies of neurodevelopmental disorders, neuroimaging abnormalities, and treatment
YP Zhou, MJ Mei, XZ Wang, SN Huang, L Chen… - JCI insight, 2022 - ncbi.nlm.nih.gov
Congenital cytomegalovirus (cCMV) infection is the leading infectious cause of
neurodevelopmental disorders. However, the neuropathogenesis remains largely elusive …
neurodevelopmental disorders. However, the neuropathogenesis remains largely elusive …
Acute cerebellar inflammation and related ataxia: mechanisms and pathophysiology
MSA Parvez, G Ohtsuki - Brain sciences, 2022 - mdpi.com
The cerebellum governs motor coordination and motor learning. Infection with external
microorganisms, such as viruses, bacteria, and fungi, induces the release and production of …
microorganisms, such as viruses, bacteria, and fungi, induces the release and production of …
Role of microglia in herpesvirus-related neuroinflammation and neurodegeneration
M Patrycy, M Chodkowski, M Krzyzowska - Pathogens, 2022 - mdpi.com
Neuroinflammation is defined as an inflammatory state within the central nervous system
(CNS). Microglia conprise the resident tissue macrophages of the neuronal tissue. Upon …
(CNS). Microglia conprise the resident tissue macrophages of the neuronal tissue. Upon …
NK/ILC1 cells mediate neuroinflammation and brain pathology following congenital CMV infection
Congenital human cytomegalovirus (cHCMV) infection of the brain is associated with a wide
range of neurocognitive sequelae. Using infection of newborn mice with mouse …
range of neurocognitive sequelae. Using infection of newborn mice with mouse …
Perinatal cerebellar injury in human and animal models
V Biran, C Verney, DM Ferriero - Neurology research …, 2012 - Wiley Online Library
Cerebellar injury is increasingly recognized through advanced neonatal brain imaging as a
complication of premature birth. Survivors of preterm birth demonstrate a constellation of …
complication of premature birth. Survivors of preterm birth demonstrate a constellation of …
Murine CMV-induced hearing loss is associated with inner ear inflammation and loss of spiral ganglia neurons
Congenital human cytomegalovirus (HCMV) occurs in 0.5–1% of live births and
approximately 10% of infected infants develop hearing loss. The mechanism (s) of hearing …
approximately 10% of infected infants develop hearing loss. The mechanism (s) of hearing …
Cytomegalovirus infection: mouse model
This unit describes procedures for infecting newborn and adult mice with murine
cytomegalovirus (MCMV). Methods are included for propagating MCMV in cell cultures and …
cytomegalovirus (MCMV). Methods are included for propagating MCMV in cell cultures and …