Central nervous system (CNS) disorders like Alzheimer's disease (AD), Parkinson disease
(PD), stroke, epilepsy, depression, and bipolar disorder have a high impact on both medical …

Modified and synthetic α‐amino acids are known to show diverse applications. Histidine,
which possesses numerous applications when subjected to synthetic modifications, is one …

The treatment options currently available for narcolepsy are often unsatisfactory due to
suboptimal efficacy, troublesome side effects, development of drug tolerance, and …

Thyrotropin-releasing hormone (TRH) is an important endocrine agent that regulates the
function of cells in the anterior pituitary and the central and peripheral nervous systems. By …

Epilepsy is one of the most prevalent and drug-refractory neurological disorders. Zinc finger
DHHC-type containing 8 (ZDHHC8) is a putative palmitoyltransferase that is highly …

Menthol is a natural compound that evokes cold sensations by activating TRPM8 channels
in peripheral sensory receptors. Little is known about the effects of this compound on brain …

Neuropeptides are signaling molecules participating in the modulation of synaptic
transmission. Neuropeptides are stored in dense core synaptic vesicles, the release of …

Objective Much evidence suggests that the subiculum plays a significant role in the
regulation of epileptic activity. Lactate acts as a neuroprotective agent against many …

Thyrotropin releasing hormone (TRH: Glp-His-Pro-NH2) is a peptide mainly produced by
brain neurons. In mammals, hypophysiotropic TRH neurons of the paraventricular nucleus of …

Capsaicin, a compound found in chili peppers, causes burning sensations by acting on the
peripheral sensory system. However, it has also been reported to exert substantial effects on …