A stay of execution: ATF4 regulation and potential outcomes for the integrated stress response

G Neill, GR Masson - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
ATF4 is a cellular stress induced bZIP transcription factor that is a hallmark effector of the
integrated stress response. The integrated stress response is triggered by phosphorylation …

A Novel Strategy for the Development of Functional Foods to Improve Energy Metabolism Disorders: Stable Isotope-Resolved Metabolomics

W Wu, Q Meng, Y Mi, F Wang, R Zhang, W Li… - Food and Bioprocess …, 2024 - Springer
With the change of people's dietary structures, obesity, diabetes, and other related chronic
metabolic diseases characterized by energy metabolism disorders have become a public …

Single-Cell RNA Sequencing (scRNA-seq) Identifies L1CAM as a Key Mediator between Epithelial Tuft Cell and Innate Lymphoid Cell in the Colon of Hnrnp I …

G Xu, YX Pan, W Mei, H Chen - Biomedicines, 2023 - mdpi.com
(1) Background: Knockout (KO) of heterogeneous nuclear ribonucleoprotein I (Hnrnp I) in
mouse intestinal epithelial cells (IECs) induced a severe inflammatory response in the colon …

Low protein diet during lactation programs hepatic metabolism in adult male and female rats

IM Bertasso, EG de Moura, CB Pietrobon… - The Journal of …, 2022 - Elsevier
The liver is an essential regulator of energy metabolism, and its function can be disrupted by
nutritional alterations. Since liver development continues during breastfeeding nutritional …

The Low Protein Diet induced Fetal Programming Leads to Mitochondrial Dysfunction and Metabolic Inflexibility in the Skeletal Muscle of Male Rats

VA Vidyadharan, A Betancourt, C Smith, CS Blesson… - 2024 - researchsquare.com
A prenatal low-protein (LP) diet disrupts glucose homeostasis in adult offspring. Skeletal
muscles are one of the main sites of glucose clearance, and mitochondria residing in the …