[HTML][HTML] The role of sphingomyelin and ceramide in motor neuron diseases

G McCluskey, C Donaghy, KE Morrison… - Journal of personalized …, 2022 - mdpi.com
Amyotrophic Lateral Sclerosis (ALS), Spinal Bulbar Muscular Atrophy (SBMA), and Spinal
Muscular Atrophy (SMA) are motor neuron diseases (MNDs) characterised by progressive …

A proteogenomic view of Parkinson's disease causality and heterogeneity

S Kaiser, L Zhang, B Mollenhauer, J Jacob… - npj Parkinson's …, 2023 - nature.com
The pathogenesis and clinical heterogeneity of Parkinson's disease (PD) have been
evaluated from molecular, pathophysiological, and clinical perspectives. High-throughput …

Defining the glucosylceramide population of C. elegans

MA Xatse, CP Olsen - Frontiers in Physiology, 2023 - frontiersin.org
Glucosylceramides (GlcCer) are lipids that impact signaling pathways, serve as critical
components of cellular membranes, and act as precursors for hundreds of other complex …

Identifying Membrane Protein–Lipid Interactions with Lipidomic Lipid Exchange-Mass Spectrometry

G Zhang, MT Odenkirk, CM Janczak… - Journal of the …, 2023 - ACS Publications
Lipids can play important roles in modulating membrane protein structure and function.
However, it is challenging to identify natural lipids bound to membrane proteins in complex …

Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease

CEG Leyns, A Prigent, B Beezhold, L Yao… - npj Parkinson's …, 2023 - nature.com
Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are progressive
neurodegenerative diseases characterized by the accumulation of misfolded α-synuclein in …

Glucosylceramide is essential for Heartland and Dabie bandavirus glycoprotein-induced membrane fusion

T Xia, X Wu, E Hong, K Jung, CJ Lai, MJ Kwak… - PLoS …, 2023 - journals.plos.org
Due to climate changes, there has been a large expansion of emerging tick-borne zoonotic
viruses, including Heartland bandavirus (HRTV) and Dabie bandavirus (DBV). As etiologic …

Studies on the novel effects of electron beam treated pollen on colony reproductive output in commercially-reared bumblebees (Bombus terrestris) for mass pollination …

J Eakins, M Lynch, JC Carolan, NJ Rowan - Science of the Total …, 2023 - Elsevier
Commercially-reared bumblebees provide an important pollinator service that helps support
food production and security. The deployment of an appropriate non-thermal disinfection …

Untargeted metabolomics identifies metabolic dysregulation of sphingolipids associated with aggressive chronic lymphocytic leukaemia and poor survival

F Nguyen Van Long… - Clinical and …, 2023 - Wiley Online Library
Background Metabolic dependencies of chronic lymphocytic leukaemia (CLL) cells may
represent new personalized treatment approaches in patients harbouring unfavourable …

[图书][B] Instrumental thin-layer chromatography

C Poole - 2023 - books.google.com
Instrumental Thin-Layer Chromatography, Second Edition offers a comprehensive source of
authoritative information on all aspects of instrumental thin-layer chromatography. The use …

Glucosylceramide in bunyavirus particles is essential for virus binding to host cells

ZM Uckeley, M Duboeuf, Y Gu, A Erny… - Cellular and Molecular …, 2024 - Springer
Hexosylceramides (HexCer) are implicated in the infection process of various pathogens.
However, the molecular and cellular functions of HexCer in infectious cycles are poorly …