Simple Summary Despite the advancements in systemic treatments, the incidence of brain
metastasis (BM) is increasing. BM is a multi-step cascade. One critical event in BM is the …

Bone metastasis is considered as a considerable challenge for breast cancer patients.
Various in vitro and in vivo models have been developed to examine this occurrence. In vitro …

Metastasis is the leading cause of cancer mortality. Metastatic cancer is notoriously difficult
to treat, and it accounts for the majority of cancer-related deaths. The ether lipid edelfosine is …

Nimbolide based nanomedicine inhibits Cancer Stem-like Cells by epigenetic
reprogramming of DNMTs-SFRP1-Wnt/β-catenin signaling Page 1 Journal Pre-proof …

Epithelial ovarian cancer (OC) is often diagnosed at an advanced stage with peritoneal
metastasis, and preclinical models mimicking the natural course of OC peritoneal metastasis …

The effect of cathelicidin hCAP18/LL-37 in hepatocellular carcinoma (HCC) metastasis
remains unclear. Here, we confirmed that LL-37 expression enhanced endothelial …

Bone tissue represents the most frequent site of cancer metastasis. We developed a
hemichannel-activating antibody, Cx43-M2. Cx43-M2, directly targeting osteocytes in situ …

Women that present to the clinic with established breast cancer metastases have limited
treatment options. Yet, the majority of preclinical studies are actually not directed at …

Gene expression analysis at the single-cell level by next-generation sequencing has
revealed the existence of clonal dissemination and microheterogeneity in cancer metastasis …

Preventing breast cancer liver metastasis presents formidable challenges with multifaceted
obstacles. In the case of acute and chronic liver injury, the disrupted liver microenvironment …