Systematic review with meta‐analysis: mycophenolate mofetil as a second‐line therapy for autoimmune hepatitis

P Santiago, I Schwartz, L Tamariz… - Alimentary …, 2019 - Wiley Online Library
Background First‐line treatment for autoimmune hepatitis (AIH) typically includes
corticosteroids in combination with azathioprine. Mycophenolate mofetil (MMF) is often used …

Autoimmune hepatitis: Current and future therapeutic options

I Doycheva, KD Watt, AF Gulamhusein - Liver International, 2019 - Wiley Online Library
Autoimmune hepatitis (AIH) is a rare immune‐mediated liver disease with few major
advances in treatment options over the last several decades. Available options are effective …

The Asian Pacific Association for the Study of the Liver clinical practice guidance: the diagnosis and management of patients with autoimmune hepatitis

G Wang, A Tanaka, H Zhao, J Jia, X Ma… - Hepatology …, 2021 - Springer
Guiqiang Wang1, 18· Atsushi Tanaka2· Hong Zhao1, 1 8· Jidong Jia3· Xiong Ma4· Kenichi
Harada5· Fu‑Sheng Wang6· Lai Wei7· Qixia Wang4· Ying Sun6· Yuan Hong1· Huiying …

[HTML][HTML] An open-label randomised-controlled trial of azathioprine vs. mycophenolate mofetil for the induction of remission in treatment-naive autoimmune hepatitis

RJ Snijders, AEC Stoelinga, TJG Gevers, S Pape… - Journal of …, 2024 - Elsevier
Background & Aims Patients with autoimmune hepatitis (AIH) almost invariably require
lifelong immunosuppressive treatment. There is genuine concern about the efficacy and …

[HTML][HTML] Immunosuppressive drugs

Y Hussain, H Khan - Encyclopedia of infection and immunity, 2022 - ncbi.nlm.nih.gov
Immunosuppressant is a class of medicines that inhibit or decrease the intensity of the
immune response in the body. Most of these medications are used to allow the body less …

[HTML][HTML] The current status of steroid-refractory immune-checkpoint-inhibitor-related hepatotoxicity

H Xing, Y Wang, B Qu, Q Wei, C Li, C Pan, H Li - Translational Oncology, 2023 - Elsevier
ICI-related hepatotoxicity (IRH) is becoming more and more common as immune checkpoint
inhibitors (ICIs) have begun to be increasingly approved and used in combination with other …

Grand round: autoimmune hepatitis

PJ Trivedi, SG Hubscher, M Heneghan, D Gleeson… - Journal of …, 2019 - Elsevier
Autoimmune hepatitis is a corticosteroid-responsive liver disease arising consequent to
immunogenetic and environmental risk factors. The clinical course reflects relapsing and …

Established and novel therapeutic options for autoimmune hepatitis

R Liberal, YS de Boer, MA Heneghan - The Lancet Gastroenterology …, 2021 - thelancet.com
Autoimmune hepatitis is an immune-mediated disorder characterised by
hypergammaglobulinaemia, autoantibodies, and interface hepatitis. The mainstay of …

[HTML][HTML] Immune tolerance induced by immune-homeostatic particles

G Chen, H Zhang, H Wang, F Wang - Engineered Regeneration, 2021 - Elsevier
Autoimmune diseases, induced by dysfunction of the adaptive immune system, are the
common disease categories worldwide. Recently, regulatory T cells (Tregs) enhancing …

Autoimmune hepatitis: Challenges and novelties

I Olivas, S Rodriguez-Tajes, MC Londoño - Medicina Clínica (English …, 2022 - Elsevier
Autoimmune hepatitis is a chronic inflammatory disease of the liver. The etiology is partly
unknown and commonly affects women of all ages. It is characterised by increase in …