Idiopathic REM sleep behaviour disorder and neurodegeneration—an update

B Högl, A Stefani, A Videnovic - Nature Reviews Neurology, 2018 - nature.com
So-called idiopathic rapid eye movement (REM) sleep behaviour disorder (RBD), formerly
seen as a rare parasomnia, is now recognized as the prodromal stage of an α …

Identifying prodromal Parkinson's disease: pre‐motor disorders in Parkinson's disease

RB Postuma, D Aarsland, P Barone… - Movement …, 2012 - Wiley Online Library
Increasing recognition that Parkinson's disease (PD) may start outside of the substantia
nigra has led to a rapidly expanding effort to define prodromal stages of PD, before motor …

Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease

BF Boeve, MH Silber, CB Saper, TJ Ferman… - Brain, 2007 - academic.oup.com
REM sleep behaviour disorder (RBD) is a parasomnia characterized by the loss of normal
skeletal muscle atonia during REM sleep with prominent motor activity accompanying …

REM sleep behavior disorder: updated review of the core features, the REM sleep behavior disorder‐neurodegenerative disease association, evolving concepts …

BF Boeve - Annals of the new York Academy of Sciences, 2010 - Wiley Online Library
Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia manifested by
vivid, often frightening dreams associated with simple or complex motor behavior during …

Mild cognitive impairment in rapid eye movement sleep behavior disorder and Parkinson's disease

JF Gagnon, M Vendette, RB Postuma… - Annals of Neurology …, 2009 - Wiley Online Library
Objective To investigate the frequency and subtypes of mild cognitive impairment (MCI) in
idiopathic rapid eye movement sleep behavior disorder (RBD) and Parkinson's disease (PD) …

REM sleep behavior disorder predicts cognitive impairment in Parkinson disease without dementia

M Vendette, JF Gagnon, A Decary… - Neurology, 2007 - AAN Enterprises
Objective: To assess the relationship between the presence of REM sleep behavior disorder
(RBD) and the cognitive profile of nondemented patients with Parkinson disease (PD) …

White and gray matter abnormalities in idiopathic rapid eye movement sleep behavior disorder: a diffusion‐tensor imaging and voxel‐based morphometry study

C Scherfler, B Frauscher, M Schocke… - Annals of …, 2011 - Wiley Online Library
Objective We applied diffusion‐tensor imaging (DTI) including measurements of mean
diffusivity (MD), a parameter of brain tissue integrity, fractional anisotropy (FA), a parameter …

Idiopathic REM sleep behaviour disorder in the development of Parkinson's disease

BF Boeve - The Lancet Neurology, 2013 - thelancet.com
Parkinson's disease is a progressive neurodegenerative disorder associated with Lewy
body disease pathology in central and peripheral nervous system structures. Although the …

Mild cognitive impairment associated with limbic and neocortical Lewy body disease: a clinicopathological study

J Molano, B Boeve, T Ferman, G Smith, J Parisi… - Brain, 2010 - academic.oup.com
There are little data on the relationship between Lewy body disease and mild cognitive
impairment syndromes. The Mayo Clinic aging and dementia databases in Rochester …

Diffusion tensor imaging in idiopathic REM sleep behavior disorder reveals microstructural changes in the brainstem, substantia nigra, olfactory region, and other …

MM Unger, M Belke, K Menzler, JT Heverhagen, B Keil… - Sleep, 2010 - academic.oup.com
Abstract Study Objectives: Idiopathic rapid eye movement sleep behavior disorder (iRBD)—
a parasomnia characterized by dream enactments—is a risk marker for the development of …