Galectins are a group of evolutionarily conserved proteins with the ability to bind β‐
galactosides through characteristic carbohydrate‐recognition domains (CRD). Galectin‐3 is …

The galectin family consists of carbohydrate (glycan) binding proteins that are expressed by
a wide variety of cells and bind to galactose-containing glycans. Galectins can be located in …

The skin contains a population of tissue-resident memory T cells (Trm) that is thought to
contribute to local tissue homeostasis and protection against environmental injuries …

Genomic approaches continue to provide unprecedented insight into the microbiome, yet
host immune interactions with diverse microbiota can be difficult to study. We therefore …

Galectins are an evolutionarily ancient family of glycan-binding proteins (GBPs) and are
found in all animals. Although they were discovered over 30 years ago, ideas about their …

Galectins are a large family of carbohydrate binding proteins with members in nearly every
lineage of multicellular life. Through tandem and en-mass genome duplications, over 15 …

Galectins (Gals) are a type of S-type lectin that are widespread and evolutionarily conserved
among metazoans, and can act as pattern recognition receptors (PRRs) to recognize …

The mucosal surfaces of fish serve as the first line of defense against the myriad of aquatic
pathogens present in the aquatic environment. The immune repertoire functioning at these …

Protein–ligand interactions serve as fundamental regulators of numerous biological
processes. Among protein–ligand pairs, glycan binding proteins (GBPs) and the glycans …

While glycans are generally displayed on the cell surface or confined within the lumen of
organelles, they can become exposed to the cytosolic milieu upon disruption of organelle …