Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

ABCA7 loss-of-function variants are associated with increased risk of Alzheimer's disease
(AD). Using ABCA7 knockout human iPSC models generated with CRISPR/Cas9, we …

Reactive oxygen species (ROS) have been described to induce a broad range of redox-
dependent signaling reactions in physiological conditions. Nevertheless, an excessive …

Neuroinflammation is a critical factor in developing and progressing numerous brain
diseases, including neurodegenerative diseases. Chronic or excessive neuroinflammation …

The potential of edible mushrooms as an unexploited treasure trove, although rarely
included in known food guidelines, is highlighted. Their role in shielding people against the …

Alzheimer's disease (AD) is the most common cause of dementia and is currently one of the
biggest public health concerns in the world. Mitochondrial dysfunction in neurons is one of …

Aging is accompanied by many changes in brain and contributes to progressive cognitive
decline. In contrast to pathological changes in brain, normal aging brain changes have …