Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism

V Cagno, P Andreozzi, M D'Alicarnasso… - Nature materials, 2018 - nature.com
Viral infections kill millions yearly. Available antiviral drugs are virus-specific and active
against a limited panel of human pathogens. There are broad-spectrum substances that …

Modified cyclodextrins as broad-spectrum antivirals

ST Jones, V Cagno, M Janeček, D Ortiz, N Gasilova… - Science …, 2020 - science.org
Viral infections kill millions of people and new antivirals are needed. Nontoxic drugs that
irreversibly inhibit viruses (virucidal) are postulated to be ideal. Unfortunately, all virucidal …

Mechanism of inactivation of influenza viruses by immobilized hydrophobic polycations

BB Hsu, S Yinn Wong, PT Hammond… - Proceedings of the …, 2011 - National Acad Sciences
N, N-Dodecyl, methyl-polyethylenimine coatings applied to solid surfaces have been shown
by us to disinfect aqueous solutions of influenza viruses. Herein we elucidate the …

[HTML][HTML] Demonstrating the persistent antibacterial efficacy of a hand sanitizer containing benzalkonium chloride on human skin at 1, 2, and 4 hours after application

SW Bondurant, CM Duley, JW Harbell - American journal of infection control, 2019 - Elsevier
Background Use of hand sanitizers has become a cornerstone in clinical practice for the
prevention of disease transmission between practitioners and patients. Traditionally, these …

Farm-and flock-level risk factors associated with Highly Pathogenic Avian Influenza outbreaks on small holder duck and chicken farms in the Mekong Delta of Viet …

KA Henning, J Henning, J Morton, NT Long… - Preventive veterinary …, 2009 - Elsevier
After 11 consecutive months of control, the Mekong Delta in Viet Nam experienced a wave of
Highly Pathogenic Avian Influenza (HPAI) H5N1 outbreaks on small holder poultry farms …

Effectiveness of common household cleaning agents in reducing the viability of human influenza A/H1N1

JS Greatorex, RF Page, MD Curran, P Digard… - PLoS …, 2010 - journals.plos.org
Background In the event of an influenza pandemic, the majority of people infected will be
nursed at home. It is therefore important to determine simple methods for limiting the spread …

[PDF][PDF] Newcastle disease virus shedding among healthy commercial chickens and its epidemiological importance

EC Okwor, DC Eze, M Umeh - 2011 - academia.edu
Newcastle disease virus (NDV), also known as Avian Paramyxovirus serotype I (APMV-1) is
an RNA virus belonging to the genus Avulavirus in the family Paramyxoviridae (Mayo …

Inactivation of infectious bursal disease and Newcastle disease viruses at temperatures below 0 C using chemical disinfectants

J Guan, M Chan, BW Brooks… - Avian diseases, 2014 - meridian.allenpress.com
This study evaluated the effectiveness of bleach, Surface Decontamination Foam (SDF), and
Virkon® in inactivating infectious bursal disease virus (IBDV) and Newcastle disease virus …

Identification of Worst-Case Model Viruses for Low and High pH Inactivation.

R Nims, S Steve Zhou, M Plavsic - BioProcessing Journal, 2017 - search.ebscohost.com
In this paper, we review the efficacy data for low and high pH inactivation of viruses in
solutions (ie, liquid inactivation) and discuss the mechanisms of action and the impact of …

Advances in antiviral drug discovery and development: Part I: Advancements in antiviral drug discovery

SK Saxena, N Mishra, R Saxena - 2009 - Future Medicine
Fusion inhibitors inhibit binding/fusion of the virus to the host cell, and thus prevent
noninfected cells from infection. They target either viral surface proteins (enfuvirtide) or cell …