Some features of the OPN protein. Indicated sites of O-glycosylation and phosphorylation
are intended to be representative; both vary (phosphorylation in particular) with the source of …

Human mesenchymal stem cells (hMSCs) are considered a promising cell source for
regenerative medicine, because they have the potential to differentiate into a variety of …

Mechanical loading is an important regulator of bone formation and bone loss. Decreased
osteoblast number and function are important cellular mechanisms by which mechanical …

A primary goal of bone research is to understand the mechanism (s) by which mechanical
forces dictate the cellular and metabolic activities of osteoblasts, the bone-forming cells …

While titanium has been clinically successful as an orthopedic or dental implant material,
performance problems still persist related to implant–bone interfacial strength and …

Abstract Dentin matrix protein 1 (DMP1) was originally postulated to be dentin specific.
Further analysis showed that DMP1 is also expressed in mature cartilage and bone. In bone …

Fracture haematoma formation is the first and foremost important stage of fracture healing. It
orchestrates the inflammatory and cellular processes leading to the formation of callus and …

Porous nano-scaffolds provide for better opportunities to restore, maintain, and improve
functions of damaged tissues and organs by facilitating tissue regeneration. Various …

Mechanical force loading exerts important effects on the skeleton by controlling bone mass
and strength. Several in vivo experimental models evaluating the effects of mechanical …

Nanoscale zeolitic imidazolate framework-8 (ZIF-8)-modified titanium (ZIF-8@ AHT) can
enhance osteogenesis in vitro. In this study, we systematically and quantitatively examined …