Autophagy is a cellular process in which proteins and organelles are engulfed in
autophagosomal vesicles and transported to the lysosome/vacuole for degradation. Protein …

Autophagy, a crucial intracellular degradation process facilitated by lysosomes, plays a
pivotal role in maintaining cellular homeostasis. The elucidation of autophagy key genes …

Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3), the mammalian ortholog of
yeast vesicular protein sorting 34 (Vps34), belongs to the phosphoinositide 3-kinase (PI3K) …

One possible strategy for modulating autophagy is to disrupt the critical protein–protein
interactions (PPIs) formed during this process. Our attention is on the autophagy-related 12 …

Autophagy is a ubiquitous pathological/physiological antioxidant cellular reaction in
eukaryotic cells. Vacuolar protein sorting 34 (Vps34 or PIK3C3), which plays a crucial role in …

Macroautophagy is a catabolic process wherein cytosolic cargo is engulfed in an
autophagosome that fuses with a lysosome to degrade the cargo for recycling. Autophagy …

The autophagy-lysosome pathway is the major route for protein and organelle clearance,
and the functional status of autophagy plays an important role in the performance of skeletal …

Regulated cell death is a form of cell death that is actively controlled by biomolecules.
Several studies have shown that regulated cell death plays a key role after spinal cord …

Toxoplasma gondii is responsible for incurable parasitic infections on a global scale. All of
parasite nutrient acquisition occurs from the host environment, representing a focal point for …

The autophagy-lysosome pathway is the major route for protein and organelle clearance,
and the functional status of autophagy plays an important role in the performance of skeletal …