[HTML][HTML] Parasite recognition and signaling mechanisms in innate immune responses to malaria
DC Gowda, X Wu - Frontiers in immunology, 2018 - frontiersin.org
Malaria caused by the Plasmodium family of parasites, especially P. falciparum and P. vivax,
is a major health problem in many countries in the tropical and subtropical regions of the …
is a major health problem in many countries in the tropical and subtropical regions of the …
Targeting aminoacyl tRNA synthetases for antimalarial drug development
Infections caused by malaria parasites place an enormous burden on the world's poorest
communities. Breakthrough drugs with novel mechanisms of action are urgently needed. As …
communities. Breakthrough drugs with novel mechanisms of action are urgently needed. As …
Biological and pathological mechanisms leading to the birth of a small vulnerable newborn
The pathway to a thriving newborn begins before conception and continues in utero with a
healthy placenta and the right balance of nutrients and growth factors that are timed and …
healthy placenta and the right balance of nutrients and growth factors that are timed and …
Prevention of malaria in pregnancy
Malaria remains one of the most preventable causes of adverse birth outcomes. Intermittent
preventive treatment in pregnancy (IPTp) with sulfadoxine–pyrimethamine is used to prevent …
preventive treatment in pregnancy (IPTp) with sulfadoxine–pyrimethamine is used to prevent …
PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study
SB Sirima, L Richert, A Chêne, AT Konate… - The Lancet Infectious …, 2020 - thelancet.com
Background PRIMVAC is a VAR2CSA-derived placental malaria vaccine candidate aiming
to prevent serious clinical outcomes of Plasmodium falciparum infection during pregnancy …
to prevent serious clinical outcomes of Plasmodium falciparum infection during pregnancy …
[HTML][HTML] The impact of infection in pregnancy on placental vascular development and adverse birth outcomes
AM Weckman, M Ngai, J Wright, CR McDonald… - Frontiers in …, 2019 - frontiersin.org
Healthy fetal development is dependent on nutrient and oxygen transfer via the placenta.
Optimal growth and function of placental vasculature is therefore essential to support in …
Optimal growth and function of placental vasculature is therefore essential to support in …
An overview of malaria in pregnancy
One hundred twenty-five million pregnant women are at risk for contracting malaria, a
preventable cause of maternal and infant morbidity and death. Malaria parasites contribute …
preventable cause of maternal and infant morbidity and death. Malaria parasites contribute …
[HTML][HTML] Global estimates of the number of pregnancies at risk of malaria from 2007 to 2020: a demographic study
V Reddy, DJ Weiss, J Rozier, FO Ter Kuile… - The Lancet Global …, 2023 - thelancet.com
Background The most recent global estimates of the number of pregnancies at risk of
Plasmodium falciparum and Plasmodium vivax malaria infection are from 2007. To inform …
Plasmodium falciparum and Plasmodium vivax malaria infection are from 2007. To inform …
[HTML][HTML] Effect of monthly intermittent preventive treatment with dihydroartemisinin–piperaquine with and without azithromycin versus monthly sulfadoxine …
Background Intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin–
piperaquine is more effective than IPTp with sulfadoxine–pyrimethamine at reducing malaria …
piperaquine is more effective than IPTp with sulfadoxine–pyrimethamine at reducing malaria …
[HTML][HTML] Improving pregnancy outcomes in low-and middle-income countries
RL Goldenberg, EM McClure, S Saleem - Reproductive health, 2018 - Springer
This paper reviews the very large discrepancies in pregnancy outcomes between high, low
and middle-income countries and then presents the medical causes of maternal mortality …
and middle-income countries and then presents the medical causes of maternal mortality …