dbPepVar: a novel cancer proteogenomics database

LM Da Cunha, P Terrematte, TDS Fiuza… - IEEE …, 2022 - ieeexplore.ieee.org
Cancers arise from the acquisition of DNA mutations, such as substitutions, deletions,
amplifications, and rearrangements. Understanding the distribution and correlation of such …

A dynamic model of pi3k/akt pathways in acute myeloid leukemia

YA Adi, F Adi-Kusumo, L Aryati… - Journal of Applied …, 2018 - Wiley Online Library
Acute myeloid leukemia (AML) is a malignant hematopoietic disorder characterized by
uncontrolled proliferation of immature myeloid cells. In the AML cases, the phosphoinositide …

Torus and Homoclinic Bifurcations on a Cells Repair Regulations Model of the Metastatic Nasopharyngeal Carcinoma

A Wiraya, F Adi-Kusumo - Journal of Nonlinear Science, 2023 - Springer
Nasopharyngeal carcinoma (NPC) is a tumor that grows on nasopharyngeal epithelial cells.
There are some proteins that play important roles in the regulation of cell repair for …

Hopf bifurcation on a cancer therapy model by oncolytic virus involving the malignancy effect and therapeutic efficacy

F Adi-Kusumo, L Aryati, S Risdayati… - … of Mathematics and …, 2020 - Wiley Online Library
We introduce a mathematical model that shows the interaction dynamics between the
uninfected and the infected cancer cell populations with oncolytic viruses for the benign and …

Can ODE gene regulatory models neglect time lag or measurement scaling?

J Hu, H Qin, X Fan - Bioinformatics, 2020 - academic.oup.com
Motivation Many ordinary differential equation (ODE) models have been introduced to
replace linear regression models for inferring gene regulatory relationships from time-course …

A mathematical modelling for estradiol influence on DNA damage response and G1/S transition phase regulations in early stage of breast cancer

MF Kusuma, F Adi-Kusumo - AIP Conference Proceedings, 2019 - pubs.aip.org
Breast cancer is a malignant disease that triggers the anomalies of the cells proliferation in
breast tissue. There are some known factors that have ability to increase someone risk to …

Reaction‐Diffusion on a Spatial Mathematical Model of Cancer Immunotherapy with Effector Cells and IL‐2 Compounds' Interactions

S Suddin, F Adi-Kusumo, L Aryati… - International Journal of …, 2021 - Wiley Online Library
Immunotherapy is one of the future treatments applicable in most cases of cancer including
malignant cancer. Malignant cancer usually prevents some genes, eg, p53 and pRb, from …

Homoclinic and torus bifurcations on cells repair regulations model of the metastatic nasopharyngeal carcinoma

F Adi-Kusumo, A Wiraya - Biomath Communications …, 2018 - biomath.math.bas.bg
We consider a mathematical model of the Nasopharyngeal Carcinoma (NPC) that grows on
the nasopharynx epithelial cell. The model shows the interaction between ATM, p53, MDM2 …