Neuronal hyperexcitability and free radical toxicity in amyotrophic lateral sclerosis: Established and future targets
K Shibuya, R Otani, Y Suzuki, S Kuwabara… - Pharmaceuticals, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a devastating disease with evidence of degeneration
involving upper and lower motor neuron compartments of the nervous system. Presently, two …
involving upper and lower motor neuron compartments of the nervous system. Presently, two …
Brain stimulation as a therapeutic tool in amyotrophic lateral sclerosis: Current status and interaction with mechanisms of altered cortical excitability
In the last 20 years, several modalities of neuromodulation, mainly based on non-invasive
brain stimulation (NIBS) techniques, have been tested as a non-pharmacological …
brain stimulation (NIBS) techniques, have been tested as a non-pharmacological …
[HTML][HTML] Cortico-spinal tDCS in amyotrophic lateral sclerosis: A randomized, double-blind, sham-controlled trial followed by an open-label phase
Background Amyotrophic lateral sclerosis (ALS) is a progressive disease for which no
curative treatment is currently available. Objective This study aimed to investigate whether …
curative treatment is currently available. Objective This study aimed to investigate whether …
Novel approaches to motoneuron disease/ALS treatment using non-invasive brain and spinal stimulation: IFCN handbook chapter
Non-invasive brain stimulation techniques have been exploited in motor neuron disease
(MND) with multifold objectives: to support the diagnosis, to get insights in the …
(MND) with multifold objectives: to support the diagnosis, to get insights in the …
Remotely supervised transcranial direct current stimulation: a feasibility study for amyotrophic lateral sclerosis
BACKGROUND: Transcranial direct current stimulation (tDCS) has been investigated as a
therapeutic neuromodulation tool in several neurological disorders. However, evidence …
therapeutic neuromodulation tool in several neurological disorders. However, evidence …
Therapeutic non-invasive brain stimulation in amyotrophic lateral sclerosis: rationale, methods and experience
The neurodegenerative syndrome amyotrophic lateral sclerosis (ALS) is characterised by
increased cortical excitability, thought to reflect pathological changes in the balance of local …
increased cortical excitability, thought to reflect pathological changes in the balance of local …