HDGF: a novel jack-of-all-trades in cancer
C Bao, J Wang, W Ma, X Wang, Y Cheng - Future Oncology, 2014 - Taylor & Francis
ABSTRACT HDGF is an important regulator of a broad range of cancer cell activities and
plays important roles in cancer cell transformation, apoptosis, angiogenesis and metastasis …
plays important roles in cancer cell transformation, apoptosis, angiogenesis and metastasis …
Hepatoma-derived growth factor: Its possible involvement in the progression of hepatocellular carcinoma
H Enomoto, H Nakamura, W Liu… - International journal of …, 2015 - mdpi.com
The development of hepatocellular carcinoma (HCC) is an important complication of viral
infection induced by hepatitis virus C, and our major research theme is to identify a new …
infection induced by hepatitis virus C, and our major research theme is to identify a new …
HDGF stimulates liver tumorigenesis by enhancing reactive oxygen species generation in mitochondria
TH Hu, JC Wu, ST Huang, TH Chu, AJ Han… - Journal of Biological …, 2023 - ASBMB
Hepatoma-derived growth factor (HDGF) overexpression and uncontrolled reactive oxygen
species (ROS) accumulation are involved in malignant transformation and poor prognosis in …
species (ROS) accumulation are involved in malignant transformation and poor prognosis in …
Defining the Akt1 interactome and its role in regulating the cell cycle
Cell growth and proliferation are two diverse processes yet always linked. Akt1, a
serine/threonine kinase, is a multi-functional protein implicated in regulation of cell growth …
serine/threonine kinase, is a multi-functional protein implicated in regulation of cell growth …
Differential proteomic analysis reveals that EGCG inhibits HDGF and activates apoptosis to increase the sensitivity of non‐small cells lung cancer to chemotherapy
A Flores‐Pérez, LA Marchat… - PROTEOMICS …, 2016 - Wiley Online Library
Purpose To search for regulated proteins in response to green tea (–)‐epigallocatechin‐3‐
gallate (EGCG) in A549 lung cancer cells. Experimental design 2DE and ESI/multistage MS …
gallate (EGCG) in A549 lung cancer cells. Experimental design 2DE and ESI/multistage MS …
The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin
Abstract HDGF-related protein 3 (HRP3, also known as HDGFL3) belongs to the family of
HDGF-related proteins (HRPs) and plays an essential role in hepatocellular carcinoma …
HDGF-related proteins (HRPs) and plays an essential role in hepatocellular carcinoma …
Downregulation of hepatoma-derived growth factor contributes to retarded lung metastasis via inhibition of epithelial–mesenchymal transition by systemic POMC gene …
HE Tsai, GS Liu, ML Kung, LF Liu, JC Wu… - Molecular cancer …, 2013 - AACR
The prognosis of malignant melanoma is poor due to high incidence of metastasis,
underscoring the demand for development of novel therapeutic strategies. Stress hormone …
underscoring the demand for development of novel therapeutic strategies. Stress hormone …
Binding Behavior of Human Hepatoma-Derived Growth Factor on SMYD1
JK Wu, Y Lee, H Hung, YP Chang… - The Journal of …, 2024 - ACS Publications
The protein-induced fluorescence change technique was employed to investigate the
interactions between proteins and their DNA substrates modified with the Cy3 fluorophore. It …
interactions between proteins and their DNA substrates modified with the Cy3 fluorophore. It …
Cyclic mechanical stretch up-regulates hepatoma-derived growth factor expression in cultured rat aortic smooth muscle cells
YH Kao, PH Chen, CK Sun, YC Chang… - Bioscience …, 2018 - portlandpress.com
Hepatoma-derived growth factor (HDGF) is a potent mitogen for vascular smooth muscle
cells (SMCs) during embryogenesis and injury repair of vessel walls. Whether mechanical …
cells (SMCs) during embryogenesis and injury repair of vessel walls. Whether mechanical …
Hepatoma-derived growth factor predicts disease severity and survival in pulmonary arterial hypertension
J Yang, MK Nies, Z Fu, R Damico… - American journal of …, 2016 - atsjournals.org
Rationale: Pulmonary arterial hypertension (PAH) is a fatal disease, and pulmonary
microvascular remodeling is an important contributor to PAH development. Therefore, we …
microvascular remodeling is an important contributor to PAH development. Therefore, we …