European academy of neurology/Movement Disorder Society‐European section guideline on the treatment of Parkinson's disease: I. Invasive therapies

G Deuschl, A Antonini, J Costa… - European Journal of …, 2022 - Wiley Online Library
Abstract Background and Purpose This update of the treatment guidelines was
commissioned by the European Academy of Neurology and the European section of the …

Neurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions

WJ Neumann, LA Steiner, L Milosevic - Brain, 2023 - academic.oup.com
Deep brain stimulation is a neuromodulatory treatment for managing the symptoms of
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …

Randomized trial of focused ultrasound subthalamotomy for Parkinson's disease

R Martínez-Fernández, JU Máñez-Miró… - … England Journal of …, 2020 - Mass Medical Soc
Background The subthalamic nucleus is the preferred neurosurgical target for deep-brain
stimulation to treat cardinal motor features of Parkinson's disease. Focused ultrasound is an …

The Movement Disorder Society Evidence‐Based Medicine Review Update: Treatments for the motor symptoms of Parkinson's disease

SH Fox, R Katzenschlager, SY Lim… - Movement …, 2011 - Wiley Online Library
The objective was to update previous evidence‐based medicine reviews of treatments for
motor symptoms of Parkinson's disease published between 2002 and 2005. Level I …

Deep brain stimulation for Parkinson disease: an expert consensus and review of key issues

JM Bronstein, M Tagliati, RL Alterman… - Archives of …, 2011 - jamanetwork.com
Objective: To provide recommendations to patients, physicians, and other health care
providers on several issues involving deep brain stimulation (DBS) for Parkinson disease …

Focused ultrasound subthalamotomy in patients with asymmetric Parkinson's disease: a pilot study

R Martínez-Fernández, R Rodríguez-Rojas… - The Lancet …, 2018 - thelancet.com
Background Ablative neurosurgery has been used to treat Parkinson's disease for many
decades. MRI-guided focused ultrasound allows focal lesions to be made in deep brain …

Behavioral theories and the neurophysiology of reward

W Schultz - Annu. Rev. Psychol., 2006 - annualreviews.org
The functions of rewards are based primarily on their effects on behavior and are less
directly governed by the physics and chemistry of input events as in sensory systems …

Treatment of motor and non-motor features of Parkinson's disease with deep brain stimulation

A Fasano, A Daniele, A Albanese - The Lancet Neurology, 2012 - thelancet.com
Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of
Parkinson's disease. Several deep brain nuclei have been stimulated, producing a wide …

Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa

Y Smith, T Wichmann, SA Factor… - …, 2012 - nature.com
The demonstration that dopamine loss is the key pathological feature of Parkinson's disease
(PD), and the subsequent introduction of levodopa have revolutionalized the field of PD …

Parkinson's D isease, the S ubthalamic N ucleus, I nhibition, and I mpulsivity

M Jahanshahi, I Obeso, C Baunez… - Movement …, 2015 - Wiley Online Library
Although Parkinson's disease (PD) is primarily considered a disorder of initiation of actions,
patients also have deficits in inhibitory control, both in the motor and cognitive domains …