Fusion of enveloped viruses in endosomes

JM White, GR Whittaker - Traffic, 2016 - Wiley Online Library
Ari Helenius launched the field of enveloped virus fusion in endosomes with a seminal
paper in the Journal of Cell Biology in 1980. In the intervening years, a great deal has been …

Cell fusion: merging membranes and making muscle

MJ Petrany, DP Millay - Trends in cell biology, 2019 - cell.com
Cell fusion is essential for the development of multicellular organisms, and plays a key role
in the formation of various cell types and tissues. Recent findings have highlighted the …

Myoblast fusion confusion: the resolution begins

SC Sampath, SC Sampath, DP Millay - Skeletal muscle, 2018 - Springer
The fusion of muscle precursor cells is a required event for proper skeletal muscle
development and regeneration. Numerous proteins have been implicated to function in …

Fusogenic reoviruses and their fusion-associated small transmembrane (FAST) proteins

R Duncan - Annual review of virology, 2019 - annualreviews.org
With no limiting membrane surrounding virions, nonenveloped viruses have no need for
membrane fusion to gain access to intracellular replication compartments. Consequently …

PackMem: a versatile tool to compute and visualize interfacial packing defects in lipid bilayers

R Gautier, A Bacle, ML Tiberti, PF Fuchs, S Vanni… - Biophysical journal, 2018 - cell.com
The analysis of the structural organization of lipid bilayers is generally performed across the
direction normal to the bilayer/water interface, whereas the surface properties of the bilayer …

FAST Proteins: Development and Use of Reverse Genetics Systems for Reoviridae Viruses

Y Kanai, T Kobayashi - Annual review of virology, 2021 - annualreviews.org
Reverse genetics systems for viruses, the technology used to generate gene-engineered
recombinant viruses from artificial genes, enable the study of the roles of the individual …

Structural insights into membrane fusion mediated by convergent small fusogens

Y Yang, NN Margam - Cells, 2021 - mdpi.com
From lifeless viral particles to complex multicellular organisms, membrane fusion is
inarguably the important fundamental biological phenomena. Sitting at the heart of …

Myomerger Induces Membrane Hemifusion and Regulates Fusion Pore Expansion

AL Di Bartolo, M Caparotta, LM Polo, D Masone - Biochemistry, 2024 - ACS Publications
Membrane fusion is a crucial mechanism in a wide variety of important events in cell biology
from viral infection to exocytosis. However, despite many efforts and much progress, cell …

Polycistronic genome segment evolution and gain and loss of FAST protein function during fusogenic orthoreovirus speciation

Y Yang, G Gaspard, N McMullen, R Duncan - Viruses, 2020 - mdpi.com
The Reoviridae family is the only non-enveloped virus family with members that use
syncytium formation to promote cell–cell virus transmission. Syncytiogenesis is mediated by …

Effect of cholesterol on the membrane partitioning dynamics of hepatitis A virus-2B peptide

S Sikdar, M Banerjee, S Vemparala - Soft Matter, 2021 - pubs.rsc.org
Understanding viral peptide detection and partitioning and the subsequent host membrane
composition-based response is essential for gaining insights into the viral mechanism. Here …