The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …

The design of artificial catalysts able to compete with the catalytic proficiency of enzymes is
an intense subject of research. Non-covalent interactions are thought to be involved in …

Darwinian evolution involves the inheritance and selection of variations in reproducing
entities. Selection can be based on, among others, interactions with the environment …

Self‐replication is a fundamental concept. The idea of an entity that can repeatedly create
more of itself has captured the imagination of many thinkers from von Neumann to …

The two-volume Encyclopedia of Supramolecular Chemistry offers authoritative, centralized
information on a rapidly expanding interdisciplinary field. User-friendly and high-quality …

Peptide C-terminal thioesters are key intermediates in a variety of applications, most notably
the recently developed native chemical ligation methods for the total chemical synthesis of …

Self-replicating chemical systems have been designed and studied to identify the minimal
requirements for molecular replication, to translate the principle into synthetic …

Several different non-enzymatic molecular replication systems have been prepared and
analyzed, including nucleic acids, fatty acids, peptides, and organic molecules.[1–11] This …

Self-replication has been demonstrated in synthetic chemical systems based on
oligonucleotides,,,,,,, peptides,,,, and complementary molecules without natural analogues …

Biological self‐assembly is very complex and results in highly functional materials. In effect,
it takes a bottom‐up approach using biomolecular building blocks of precisely defined …