MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …

Inflammation is a biological response of the immune system to various insults, such as
pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro …

Here we conducted a large-scale genetic association analysis of educational attainment in a
sample of approximately 1.1 million individuals and identify 1,271 independent genome …

Host dependency factors that are required for influenza A virus infection may serve as
therapeutic targets as the virus is less likely to bypass them under drug-mediated selection …

Recruitment of DNA repair proteins to DNA damage sites is a critical step for DNA repair.
Post-translational modifications of proteins at DNA damage sites serve as DNA damage …

Translation initiation of most mammalian mRNAs is mediated by a 5′ cap structure that
binds eukaryotic initiation factor 4E (eIF4E). However, inactivation of eIF4E does not impair …

MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …

microRNAs (miRs) are emerging as attractive therapeutic targets because of their small size,
specific targetability, and critical role in disease pathogenesis. However,< 20 miR targeting …

Chemical biology has revealed the importance of sialic acids as a major signal in physiology
and disease. The terminal modification α-2, 6-sialic acid is controlled by the enzymes …

Eukaryotic translation initiation relies on the m 7 G cap present at the 5′ end of all mRNAs.
Some viral mRNAs employ alternative mechanisms of initiation based on internal ribosome …