[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

Lung MRI with hyperpolarised gases: current & future clinical perspectives

NJ Stewart, LJ Smith, HF Chan… - The British Journal of …, 2022 - academic.oup.com
The use of pulmonary MRI in a clinical setting has historically been limited. Whilst CT
remains the gold-standard for structural lung imaging in many clinical indications, technical …

Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

[HTML][HTML] Hyperpolarized 129Xe for investigation of mild cystic fibrosis lung disease in pediatric patients

RP Thomen, LL Walkup, DJ Roach, ZI Cleveland… - Journal of Cystic …, 2017 - Elsevier
Background Cystic fibrosis (CF) is a genetic disease which carries high morbidity and
mortality from lung-function decline. Monitoring disease progression and treatment response …

Comparison of 3He and 129Xe MRI for evaluation of lung microstructure and ventilation at 1.5T

NJ Stewart, HF Chan, PJC Hughes… - Journal of magnetic …, 2018 - Wiley Online Library
Background To support translational lung MRI research with hyperpolarized 129Xe gas,
comprehensive evaluation of derived quantitative lung function measures against …

3D diffusion‐weighted 129Xe MRI for whole lung morphometry

HF Chan, NJ Stewart, G Norquay… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose To obtain whole lung morphometry measurements from 129Xe in a single breath‐
hold with 3D multiple b‐value 129Xe diffusion‐weighted MRI (DW‐MRI) with an empirically …

Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report

CCW Hsia, JHT Bates, B Driehuys, SB Fain… - Annals of the …, 2023 - atsjournals.org
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Quantification of pulmonary functional MRI: state-of-the-art and emerging image processing methods and measurements

M Sharma, PV Wyszkiewicz… - Physics in Medicine …, 2022 - iopscience.iop.org
Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …

Using imaging as a biomarker for asthma

A Trivedi, C Hall, EA Hoffman, JC Woods… - Journal of Allergy and …, 2017 - Elsevier
There have been significant advancements in the various imaging techniques being used
for the evaluation of asthmatic patients, both from a clinical and research perspective …

Airway Microstructure in Idiopathic Pulmonary Fibrosis: Assessment at Hyperpolarized 3He Diffusion-weighted MRI

HF Chan, ND Weatherley, CS Johns, NJ Stewart… - Radiology, 2019 - pubs.rsna.org
Background MRI with inhaled hyperpolarized helium 3 (3He) allows for functional and
structural imaging of the lungs. Hyperpolarized gas diffusion-weighted (DW) MRI provides …