[HTML][HTML] Natural sweetener Stevia rebaudiana: Functionalities, health benefits and potential risks

V Peteliuk, L Rybchuk, M Bayliak, KB Storey… - EXCLI …, 2021 - ncbi.nlm.nih.gov
Stevia rebaudiana is a South American plant, the cultivation of which is increasing
worldwide due to its high content of sweet compounds. Stevia sweetness is mainly due to …

Regulation of immune responses by tuft cells

C Schneider, CE O'Leary, RM Locksley - Nature Reviews Immunology, 2019 - nature.com
Tuft cells are rare, secretory epithelial cells that generated scant immunological interest until
contemporaneous reports in 2016 linked tuft cells with type 2 immunity in the small intestine …

[HTML][HTML] Stevia leaf to stevia sweetener: exploring its science, benefits, and future potential

P Samuel, KT Ayoob, BA Magnuson… - The Journal of …, 2018 - Elsevier
Steviol glycoside sweeteners are extracted and purified from the Stevia rebaudiana Bertoni
plant, a member of the Asteraceae (Compositae) family that is native to South America …

Infection by the parasitic helminth Trichinella spiralis activates a Tas2r-mediated signaling pathway in intestinal tuft cells

XC Luo, ZH Chen, JB Xue, DX Zhao… - Proceedings of the …, 2019 - National Acad Sciences
The parasitic helminth Trichinella spiralis, which poses a serious health risk to animals and
humans, can be found worldwide. Recent findings indicate that a rare type of gut epithelial …

Plant-based antidiabetic nanoformulations: the emerging paradigm for effective therapy

S Dewanjee, P Chakraborty, B Mukherjee… - International journal of …, 2020 - mdpi.com
Diabetes mellitus is a life-threatening metabolic syndrome. Over the past few decades, the
incidence of diabetes has climbed exponentially. Several therapeutic approaches have …

The triggering pathway to insulin secretion: Functional similarities and differences between the human and the mouse β cells and their translational relevance

M Skelin Klemen, J Dolenšek, M Slak Rupnik, A Stožer - Islets, 2017 - Taylor & Francis
In β cells, stimulation by metabolic, hormonal, neuronal, and pharmacological factors is
coupled to secretion of insulin through different intracellular signaling pathways. Our …

[HTML][HTML] Beta-cell ion channels and their role in regulating insulin secretion

B Thompson, LS Satin - Comprehensive physiology, 2021 - ncbi.nlm.nih.gov
Beta cells of the pancreatic islet express many different types of ion channels. These
channels reside in the β-cell plasma membrane as well as subcellular organelles and their …

Effect of steviol glycosides on human health with emphasis on type 2 diabetic biomarkers: a systematic review and meta-analysis of randomized controlled trials

CCB Anker, S Rafiq, PB Jeppesen - Nutrients, 2019 - mdpi.com
The natural sweetener from Stevia rebaudiana Bertoni, steviol glycoside (SG), has been
proposed to exhibit a range of antidiabetic properties. The objective of this systematic review …

The chromosome-level Stevia genome provides insights into steviol glycoside biosynthesis

X Xu, H Yuan, X Yu, S Huang, Y Sun… - Horticulture …, 2021 - academic.oup.com
Abstract Stevia (Stevia rebaudiana Bertoni) is well known for its very sweet steviol
glycosides (SGs) consisting of a common tetracyclic diterpenoid steviol backbone and a …

Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides

J Zhang, M Tang, Y Chen, D Ke, J Zhou, X Xu… - Nature …, 2021 - nature.com
Steviol glycosides are the intensely sweet components of extracts from Stevia rebaudiana.
These molecules comprise an invariant steviol aglycone decorated with variable glycans …