Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions
A Dey, R Bhattacharya, A Mukherjee… - Biotechnology advances, 2017 - Elsevier
Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …
associated with memory and cognition impairment ultimately leading to death. It is the …
Plant alkaloids as drug leads for Alzheimer's disease
YP Ng, TCT Or, NY Ip - Neurochemistry international, 2015 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative illness associated with dementia and is
most prevalent among the elderly population. Current medications can only treat symptoms …
most prevalent among the elderly population. Current medications can only treat symptoms …
[HTML][HTML] Role of plant derived alkaloids and their mechanism in neurodegenerative disorders
Neurodegenerative diseases are conventionally demarcated as disorders with selective loss
of neurons. Conventional as well as newer molecules have been tested but they offer just …
of neurons. Conventional as well as newer molecules have been tested but they offer just …
Medicinal uses, phytochemistry and pharmacology of the genus Uncaria
Q Zhang, JJ Zhao, J Xu, F Feng, W Qu - Journal of Ethnopharmacology, 2015 - Elsevier
Abstract Ethnopharmacological relevance The genus Uncaria belongs to the family
Rubiaceae, which mainly distributed in tropical regions, such as Southeast Asia, Africa and …
Rubiaceae, which mainly distributed in tropical regions, such as Southeast Asia, Africa and …
Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry
N Qin, X Lu, Y Liu, Y Qiao, W Qu, F Feng… - European Journal of …, 2021 - Elsevier
Medicinal plants are well-known in affording clinically useful agents, with rich medicinal
values by combining with disease targets through various mechanisms. Plant secondary …
values by combining with disease targets through various mechanisms. Plant secondary …
The Main Alkaloids in Uncaria rhynchophylla and Their Anti-Alzheimer's Disease Mechanism Determined by a Network Pharmacology Approach
P Zeng, XM Wang, CY Ye, HF Su, Q Tian - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is a growing concern in modern society, and effective drugs for its
treatment are lacking. Uncaria rhynchophylla (UR) and its main alkaloids have been studied …
treatment are lacking. Uncaria rhynchophylla (UR) and its main alkaloids have been studied …
Traditional Chinese medicine for anti-Alzheimer's disease: berberine and evodiamine from Evodia rutaecarpa
Z Fang, Y Tang, J Ying, C Tang, Q Wang - Chinese medicine, 2020 - Springer
Alzheimer's disease (AD) is one of the most common diseases in elderly people with a high
incidence of dementia at approximately 60–80%. The pathogenesis of AD was quite …
incidence of dementia at approximately 60–80%. The pathogenesis of AD was quite …
Protective role of Dihydromyricetin in Alzheimer's disease rat model associated with activating AMPK/SIRT1 signaling pathway
P Sun, JB Yin, LH Liu, J Guo, SH Wang… - Bioscience …, 2019 - portlandpress.com
The aim of the present study was to understand the possible role of the Dihydromyricetin
(DHM) in Alzheimer's disease (AD) rat model through regulation of the AMPK/SIRT1 …
(DHM) in Alzheimer's disease (AD) rat model through regulation of the AMPK/SIRT1 …
Regulation of mitochondrial dysfunction induced cell apoptosis is a potential therapeutic strategy for herbal medicine to treat neurodegenerative diseases
RL Li, LY Wang, HX Duan, Q Zhang, X Guo… - Frontiers in …, 2022 - frontiersin.org
Neurodegenerative disease is a progressive neurodegeneration caused by genetic and
environmental factors. Alzheimer's disease (AD), Parkinson's disease (PD), and …
environmental factors. Alzheimer's disease (AD), Parkinson's disease (PD), and …