Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging

O Veiseh, JW Gunn, M Zhang - Advanced drug delivery reviews, 2010 - Elsevier
Magnetic nanoparticles (MNPs) represent a class of non-invasive imaging agents that have
been developed for magnetic resonance (MR) imaging. These MNPs have traditionally been …

Synthesis, functionalization, and design of magnetic nanoparticles for theranostic applications

J Mosayebi, M Kiyasatfar… - Advanced Healthcare …, 2017 - Wiley Online Library
In order to translate nanotechnology into medical practice, magnetic nanoparticles (MNPs)
have been presented as a class of non‐invasive nanomaterials for numerous biomedical …

Macrophage-mimic shape changeable nanomedicine retained in tumor for multimodal therapy of breast cancer

R Liu, Y An, W Jia, Y Wang, Y Wu, Y Zhen, J Cao… - Journal of Controlled …, 2020 - Elsevier
The current nanomedicines for cancer therapy based on the enhance permeability and
retention (EPR) effect remain insufficient to satisfy the clinical need, and the challenges …

Synthesis, functionalization, and biomedical applications of multifunctional magnetic nanoparticles

R Hao, R Xing, Z Xu, Y Hou, S Gao… - Advanced materials, 2010 - Wiley Online Library
Synthesis of multifunctional magnetic nanoparticles (MFMNPs) is one of the most active
research areas in advanced materials. MFMNPs that have magnetic properties and other …

Nanocarriers' entry into the cell: relevance to drug delivery

H Hillaireau, P Couvreur - Cellular and molecular life sciences, 2009 - Springer
Nanocarriers offer unique possibilities to overcome cellular barriers in order to improve the
delivery of various drugs and drug candidates, including the promising therapeutic …

Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles

HY Nam, SM Kwon, H Chung, SY Lee, SH Kwon… - Journal of controlled …, 2009 - Elsevier
Polymeric nanoparticle-based carriers are promising agents for the targeted delivery of
therapeutics to the intracellular site of action. To optimize the efficacy in delivery, often the …

Nanoplatforms for targeted molecular imaging in living subjects

W Cai, X Chen - Small, 2007 - Wiley Online Library
Molecular or personalized medicine is the future of patient management and molecular
imaging plays a key role towards this goal. Recently, nanoplatform‐based molecular …

Nanovehicular intracellular delivery systems

A Prokop, JM Davidson - Journal of pharmaceutical sciences, 2008 - Elsevier
This article provides an overview of principles and barriers relevant to intracellular drug and
gene transport, accumulation and retention (collectively called as drug delivery) by means of …

New views on cellular uptake and trafficking of manufactured nanoparticles

L Treuel, X Jiang, GU Nienhaus - Journal of the Royal …, 2013 - royalsocietypublishing.org
Nanoparticles (NPs) are of similar size to typical cellular components and proteins, and can
efficiently intrude living cells. A detailed understanding of the involved processes at the …

Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells

O Harush-Frenkel, E Rozentur, S Benita… - …, 2008 - ACS Publications
A major challenge in drug delivery is the internalization through the apical plasma
membrane of the polarized epithelial cells lining organs facing the external environment, eg …