Diabetes is the most prevalent metabolic disturbance disease and has been regarded
globally as one of the principal causes of mortality. Diabetes is accompanied by several …

Metformin is the most commonly used treatment to increase insulin sensitivity in insulin-
resistant (IR) conditions such as diabetes, prediabetes, polycystic ovary syndrome, and …

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age. Despite its incidence, the syndrome is poorly understood and remains …

Objective. Metformin is an important component of PCOS treatment. At present, the effect of
metformin in overweight women with PCOS has not been evaluated. Therefore, we …

Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases causing
infertility in women of childbearing age. It is characterized by hyperandrogenemia (HA) …

Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder characterized by
chronic low-grade inflammation. Previous studies have demonstrated that the gut …

DNA methylation and long noncoding RNAs (lncRNAs) exhibit an indispensable role in
follicular development. However, the specific mechanisms regarding lncRNAs mediated by …

Insulin resistance (IR) disrupts ovarian functions in polycystic ovary syndrome (PCOS). The
contributing factors remains elusive. High mobility group box 1 (HMGB1), a damage …

Polycystic ovary syndrome (PCOS) is known as the most common metabolic/endocrine
disorder among women of reproductive age. Its complicated causality assessment and …

Mammalian reproductive health affects the entire reproductive cycle starting with the ovarian
function through implantation and fetal growth. Various environmental and physiological …