Recent research on flavonoids and their biomedical applications

K Wen, X Fang, J Yang, Y Yao… - Current Medicinal …, 2021 - ingentaconnect.com
Flavonoids, commonly found in various plants, are a class of polyphenolic compounds
having a basic structural unit of 2-phenylchromone. Flavonoid compounds have attracted …

The Second Life of Citrus Fruit Waste: A Valuable Source of Bioactive Compounds

C Russo, A Maugeri, GE Lombardo, L Musumeci… - Molecules, 2021 - mdpi.com
Citrus fruits (CF) are among the most widely cultivated fruit crops throughout the world and
their production is constantly increasing along with consumers' demand. Therefore, huge …

Nutraceuticals and cancer: Potential for natural polyphenols

J Maiuolo, M Gliozzi, C Carresi, V Musolino… - Nutrients, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, associated with multifactorial
pathophysiological components. In particular, genetic mutations, infection or inflammation …

Targets involved in the anti-cancer activity of quercetin in breast, colorectal and liver neoplasms

A Maugeri, A Calderaro, GT Patanè, M Navarra… - International Journal of …, 2023 - mdpi.com
Phytochemicals have long been effective partners in the fight against several diseases,
including cancer. Among these, flavonoids are valuable allies for both cancer prevention …

Oxidative stress and antioxidants in atherosclerosis development and treatment

AV Poznyak, AV Grechko, VA Orekhova… - Biology, 2020 - mdpi.com
Atherosclerosis can be regarded as chronic inflammatory disease affecting the arterial wall.
Despite the recent progress in studying the pathogenesis of atherosclerosis, some of the …

Therapeutic effects of antibiotics loaded cellulose nanofiber and κ-carrageenan oligosaccharide composite hydrogels for periodontitis treatment

A Johnson, F Kong, S Miao, HTV Lin, S Thomas… - Scientific Reports, 2020 - nature.com
Periodontitis is an inflammatory disease that can lead to the periodontal pocket formation
and tooth loss. This study was aimed to develop antimicrobials loaded hydrogels composed …

Molecular pathways involved in the anti-cancer activity of flavonols: a focus on myricetin and kaempferol

MR Felice, A Maugeri, G De Sarro, M Navarra… - International Journal of …, 2022 - mdpi.com
Natural compounds have always represented valuable allies in the battle against several
illnesses, particularly cancer. In this field, flavonoids are known to modulate a wide panel of …

Citrus fruits and their flavonoids in inflammatory bowel disease: an overview

L Musumeci, A Maugeri, S Cirmi… - Natural Product …, 2020 - Taylor & Francis
Inflammatory bowel disease (IBD), with its major manifestations being Crohn's disease and
ulcerative colitis, belongs to the gastrointestinal inflammatory disorders, whose main …

Hidrox® Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model

R Fusco, AT Salinaro, R Siracusa, R D'Amico… - Antioxidants, 2021 - mdpi.com
Background: Every year, men use cyclophosphamide to treat various cancers and
autoimmune diseases. On the one hand, this chemotherapy often has the beneficial effect of …

Enrichment of cookies with fruits and their by-products: Chemical composition, antioxidant properties, and sensory changes

A Krajewska, D Dziki - Molecules, 2023 - mdpi.com
Cookies made from wheat have become increasingly popular as a snack due to their
various advantages, such as their convenience as a ready-to-eat and easily storable food …