[HTML][HTML] Targeting oxidative stress in disease: Promise and limitations of antioxidant therapy
HJ Forman, H Zhang - Nature Reviews Drug Discovery, 2021 - nature.com
Oxidative stress is a component of many diseases, including atherosclerosis, chronic
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …
Hypertension and aging
TW Buford - Ageing research reviews, 2016 - Elsevier
Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …
of hypertension is greatest among older adults. Traditional discussions of hypertension have …
[HTML][HTML] Oxidative stress in obesity: a critical component in human diseases
L Marseglia, S Manti, G D'Angelo, A Nicotera… - International journal of …, 2014 - mdpi.com
Obesity, a social problem worldwide, is characterized by an increase in body weight that
results in excessive fat accumulation. Obesity is a major cause of morbidity and mortality and …
results in excessive fat accumulation. Obesity is a major cause of morbidity and mortality and …
A Combination Therapy Using Electrical Stimulation and Adaptive, Conductive Hydrogels Loaded with Self‐Assembled Nanogels Incorporating Short Interfering RNA …
H Lei, D Fan - Advanced Science, 2022 - Wiley Online Library
In addition to oxidative stress and impaired angiogenesis, the overexpression of
metalloproteinases (MMPs) and proinflammatory cytokines, which are promoted by …
metalloproteinases (MMPs) and proinflammatory cytokines, which are promoted by …
Reactive oxygen species (ROS)-responsive biomaterials mediate tissue microenvironments and tissue regeneration
Y Yao, H Zhang, Z Wang, J Ding, S Wang… - Journal of Materials …, 2019 - pubs.rsc.org
Reactive oxygen species (ROS) have been considered the pivotal signaling molecules in
many physiological processes, and are usually overproduced in various inflammatory …
many physiological processes, and are usually overproduced in various inflammatory …
What is the concentration of hydrogen peroxide in blood and plasma?
HJ Forman, A Bernardo, KJA Davies - Archives of biochemistry and …, 2016 - Elsevier
The concentration of hydrogen peroxide (H 2 O 2) in blood and plasma is a measurement
that has often been made, but the absolute values remain unsettled due the great variability …
that has often been made, but the absolute values remain unsettled due the great variability …
Oxidative stress alters global histone modification and DNA methylation
The JmjC domain-containing histone demethylases can remove histone lysine methylation
and thereby regulate gene expression. The JmjC domain uses iron Fe (II) and α …
and thereby regulate gene expression. The JmjC domain uses iron Fe (II) and α …
[HTML][HTML] The role of oxidative stress in the pathophysiology of hypertension
R Rodrigo, J González, F Paoletto - Hypertension Research, 2011 - nature.com
Hypertension is considered to be the most important risk factor in the development of
cardiovascular disease. An increasing body of evidence suggests that oxidative stress …
cardiovascular disease. An increasing body of evidence suggests that oxidative stress …
[HTML][HTML] Reactive oxygen species and vascular biology: implications in human hypertension
RM Touyz, AM Briones - Hypertension research, 2011 - nature.com
Increased vascular production of reactive oxygen species (ROS; termed oxidative stress)
has been implicated in various chronic diseases, including hypertension. Oxidative stress is …
has been implicated in various chronic diseases, including hypertension. Oxidative stress is …
NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities
TM Paravicini, RM Touyz - Diabetes care, 2008 - Am Diabetes Assoc
Reactive oxygen species (ROS) influence many physiological processes including host
defense, hormone biosynthesis, fertilization, and cellular signaling. Increased ROS …
defense, hormone biosynthesis, fertilization, and cellular signaling. Increased ROS …