Emerging roles of the epitranscriptome in parasitic protozoan biology and pathogenesis
G Guo, Y Lin, X Zhu, F Ding, X Xue, Q Zhang - Trends in parasitology, 2024 - cell.com
RNA modifications (epitranscriptome)–such as N6-methyladenosine (m6A), 5-
methylcytosine (m5C), and pseudouridine (Ψ)–modulate RNA processing, stability …
methylcytosine (m5C), and pseudouridine (Ψ)–modulate RNA processing, stability …
A contemporary review of snoRNAs in cardiovascular health: RNA modification and beyond
As cardiovascular diseases continue to be the leading cause of death worldwide,
groundbreaking research is currently being conducted to mitigate their effects. This review …
groundbreaking research is currently being conducted to mitigate their effects. This review …
Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification
KS Rajan, S Aryal, DG Hiregange, A Bashan… - Cell Reports, 2024 - cell.com
Leishmania is the causative agent of cutaneous and visceral diseases affecting millions of
individuals worldwide. Pseudouridine (Ψ), the most abundant modification on rRNA …
individuals worldwide. Pseudouridine (Ψ), the most abundant modification on rRNA …
[HTML][HTML] Transcript tinkering: RNA modifications in protozoan parasites
T Vignolini, JEC Couble, GRG Doré… - Current Opinion in …, 2024 - Elsevier
Highlights•Protozoan parasites encode a diverse and dynamic 'epitranscriptome'.•mRNA
modifications mediate unique mechanisms across a parasite's life cycle.•RNA modifications …
modifications mediate unique mechanisms across a parasite's life cycle.•RNA modifications …
[HTML][HTML] mt-LAF3 is a pseudouridine synthase ortholog required for mitochondrial rRNA and mRNA gene expression in Trypanosoma brucei
SM McDermott, V Pham, I Lewis, M Tracy… - International Journal for …, 2023 - Elsevier
Trypanosoma brucei and related kinetoplastid parasites possess unique RNA processing
pathways, including in their mitochondria, that regulate metabolism and development …
pathways, including in their mitochondria, that regulate metabolism and development …