Prodrug approaches for the development of a long-acting drug delivery systems

ST Chien, IT Suydam, KA Woodrow - Advanced Drug Delivery Reviews, 2023 - Elsevier
Long-acting formulations are designed to reduce dosing frequency and simplify dosing
schedules by providing an extended duration of action. One approach to obtain long-acting …

Design of biomaterials through direct ring-opening metathesis polymerisation of functionalised cyclic alkenes

S Kobayashi, M Tanaka - Molecular Systems Design & Engineering, 2023 - pubs.rsc.org
Ring-opening metathesis polymerisation (ROMP) has become a popular method for
synthesising complex functional polymers owing to the high functional group tolerance of …

ROS-responsive camptothecin-linked thioketal drug delivery system based on ring-closing polymerization

J Mathew, TN Le, HP Pham, P Kumar, CK Lee… - European Polymer …, 2024 - Elsevier
This study develops a drug delivery system that is ROS-responsive and can be triggered by
endogenous ROS. A polyethylene glycol (PEG) tail end is attached to a ring-closing polymer …

Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation

A Thakur, YH Chu, NV Rao, J Mathew… - European Journal of …, 2024 - Elsevier
Careful recruitment of the components of the HDAC inhibitory template culminated in
veliparib-based anilide 8 that elicited remarkable cell growth inhibitory effects against HL-60 …

A BODIPY‐Based Molecular Rotor in Giant Unilamellar Vesicles: A Case Study by Polarization‐Resolved Time‐Resolved Emission and Transient Absorption …

KK Jha, A Prabhakaran, L Spantzel, RC Sia… - …, 2023 - Wiley Online Library
BODIPY and BODIPY‐derived systems are widely applied as fluorophores and as probes for
viscosity detection in solvents and biological media. Their orientational and rotational …

Polynorbornene-derived block copolymer micelles via ring‐opening metathesis polymerization with capacity of hydrogen sulfide generation

TN Le, H Ru, CK Lee, NV Rao - European Polymer Journal, 2022 - Elsevier
Abstract Hydrogen sulfide (H 2 S), a gasotransmitter, has recently attracted significant
attention for its therapeutic properties. In order to achieve controlled H 2 S release, polymer …

Triplet-triplet annihilation upconversion in polymeric systems and model membranes

K Jha - 2023 - db-thueringen.de
Triplet-triplet annihilation upconversion (TTAUC) is gaining prominence in the field of optical
spectroscopy and holds the potential to revolutionize various emerging technologies such …