The production and use of antibiotics are becoming increasingly common worldwide, and
the problem of antibiotic resistance is increasing alarmingly. Drug‐resistant infections …

Highlights•The human gut microbiome harbours antibiotic resistance genes ('the
resistome').•Antibiotic resistance genes can spread in the gut microbiome through horizontal …

Background There is limited data on antibiotic treatment in hospitalized neonates in low-and
middle-income countries (LMICs). We aimed to describe patterns of antibiotic use …

Summary Background Carbapenem-resistant Enterobacterales (CRE) are a global threat.
We aimed to describe the clinical and molecular characteristics of Centers for Disease …

High-resistance rates in carbapenem-resistant GNB in many countries will inevitably
complicate treatment of serious infections in vulnerable patient groups and should …

Background Bloodstream infections comprise a wide variety of pathogens and clinical
syndromes with considerable overlap with similar syndromes of non-bacteraemic infections …

Background Bloodstream infections (BSIs) produced by antibiotic-resistant bacteria (ARB)
cause a substantial disease burden worldwide. However, most estimates come from high …

To estimate the incidence of carbapenem-resistant Enterobacterales (CRE), a global
collection of 81,781 surveillance isolates of Enterobacterales collected from patients in 39 …

Infections by multidrug-resistant (MDR) Gram-negative organisms (GN) are associated with
a high mortality rate and present an increasing challenge to the healthcare system …

Recently, the drawbacks arising from the overuse of antibiotics have drawn growing public
attention. Among them, drug-resistance (DR) and even multidrug-resistance (MDR) pose …