[HTML][HTML] In vitro and in vivo evaluation of AFB1 and OTA-toxicity through immunofluorescence and flow cytometry techniques: A systematic review

M Frangiamone, A Cimbalo, M Alonso-Garrido… - Food and Chemical …, 2022 - Elsevier
Due to the globalization, mycotoxins have been considered a major risk to human health
being the main contaminants of foodstuffs. Among them, AFB1 and OTA are the most toxic …

Risk assessment of ochratoxin A in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA to update their 2006 opinion on ochratoxin
A (OTA) in food. OTA is produced by fungi of the genus Aspergillus and Penicillium and …

Ochratoxin A–induced genotoxic and epigenetic mechanisms lead to Alzheimer disease: its modulation with strategies

K Niaz, SZA Shah, F Khan, M Bule - Environmental Science and Pollution …, 2020 - Springer
Ochratoxin A (OTA) is a naturally occurring mycotoxin mostly found in food items including
grains and coffee beans. It induces DNA single-strand breaks and has been considered to …

Intelligent photothermal dendritic cells restart the cancer immunity cycle through enhanced immunogenic cell death

Z Sun, G Deng, X Peng, X Xu, L Liu, J Peng, Y Ma… - Biomaterials, 2021 - Elsevier
Dendritic cells (DCs) play a pivotal role in initiating antigen-specific tumor immunity.
However, the abnormal function of DCs owing to the immunosuppressive tumor …

A Newly Isolated Alcaligenes faecalis ANSA176 with the Capability of Alleviating Immune Injury and Inflammation through Efficiently Degrading Ochratoxin A

R Zheng, H Qing, Q Ma, X Huo, S Huang, L Zhao… - Toxins, 2022 - mdpi.com
Ochratoxin A (OTA) is one of the most prevalent mycotoxins that threatens food and feed
safety. Biodegradation of OTA has gained much attention. In this study, an Alcaligenes …

Ochratoxin A induces nephrotoxicity and immunotoxicity through different MAPK signaling pathways in PK15 cells and porcine primary splenocytes

F Gan, Y Zhou, L Hou, G Qian, X Chen, K Huang - Chemosphere, 2017 - Elsevier
Ochratoxin A (OTA) is reported to be a potent nephrotoxin and immunotoxin in animals and
humans. However, the mechanisms underlying OTA toxicity have not been clearly …

Effects of ochratoxin A on ER stress, MAPK signaling pathway and autophagy of kidney and spleen in pigs

F Gan, L Hou, Y Zhou, Y Liu, D Huang… - Environmental …, 2017 - Wiley Online Library
Ochratoxin A (OTA), a worldwide mycotoxin found in food and feeds, is a potent nephrotoxin
and immunotoxin in animals and humans. This research was conducted to evaluate whether …

Discussion on emergency management of food safety from the perspective of foodborne diseases caused by mycotoxins

M YU, P Liu - Food Science and Technology, 2023 - SciELO Brasil
Mycotoxins exists in foods such as grains, vegetables, fruits, milk, nuts, and meat, which can
cause foodborne illnesses seriously harmful to human health. However, people have not …

Ochratoxin A and Citrinin Differentially Modulate Bovine Mammary Epithelial Cell Permeability and Innate Immune Function

R Xu, UK Shandilya, A Yiannikouris, NA Karrow - Toxins, 2022 - mdpi.com
Frequent detection of mycotoxins ochratoxin A (OTA) and citrinin (CIT) in ruminant feed and
feedstuff can be a potential threat to feed safety, animal performance and health. Ineffective …

Assessment of toxic effects of ochratoxin a in human embryonic stem cells

S Erceg, EM Mateo, I Zipancic, FJ Rodríguez Jiménez… - Toxins, 2019 - mdpi.com
Ochratoxin A (OTA) is a mycotoxin produced by different Aspergillus and Penicillium
species, and it is considered a common contaminant in food and animal feed worldwide. On …