Progress in organocatalytic asymmetric (4+ 3) cycloadditions for the enantioselective construction of seven-membered rings
W Tan, JY Zhang, CH Gao, F Shi - Science China Chemistry, 2023 - Springer
Chiral seven-membered ring systems such as seven-membered carbocycles and
heterocycles are widely found in natural products and pharmaceuticals. Therefore, the …
heterocycles are widely found in natural products and pharmaceuticals. Therefore, the …
Chemodivergent reactions
IP Beletskaya, C Nájera, M Yus - Chemical Society Reviews, 2020 - pubs.rsc.org
An important strategy for the efficient generation of diversity in molecular structures is the
utilization of common starting materials in chemodivergent transformations. The most …
utilization of common starting materials in chemodivergent transformations. The most …
Formal [4+ 1] annulation reactions in the synthesis of carbocyclic and heterocyclic systems
JR Chen, XQ Hu, LQ Lu, WJ Xiao - Chemical reviews, 2015 - ACS Publications
The development of new strategies and chemical reactions continues to be a major focus of
research efforts in the modern synthetic organic community. 1 Of the various types of …
research efforts in the modern synthetic organic community. 1 Of the various types of …
Switchable divergent asymmetric synthesis via organocatalysis
G Zhan, W Du, YC Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
The development of switchable chemo-, regio-, or diastereodivergent reactions, in which two
or more structurally and stereogenically different types of chiral products could be produced …
or more structurally and stereogenically different types of chiral products could be produced …
DMSO as a C1 Source for [2 + 2 + 1] Pyrazole Ring Construction via Metal-Free Annulation with Enaminones and Hydrazines
H Guo, L Tian, Y Liu, JP Wan - Organic Letters, 2021 - ACS Publications
A cascade reaction between enaminones, hydrazines, and dimethyl sulfoxide (DMSO) for
the synthesis of 1, 4-disubstituted pyrazoles catalyzed by molecular iodine in the presence …
the synthesis of 1, 4-disubstituted pyrazoles catalyzed by molecular iodine in the presence …
Modelling chemical reasoning to predict and invent reactions
MHS Segler, MP Waller - Chemistry–A European Journal, 2017 - Wiley Online Library
The ability to reason beyond established knowledge allows organic chemists to solve
synthetic problems and invent novel transformations. Herein, we propose a model that …
synthetic problems and invent novel transformations. Herein, we propose a model that …
Organocatalysis: A brief overview on its evolution and applications
VG Oliveira, MFC Cardoso, LSM Forezi - Catalysts, 2018 - mdpi.com
The use of small organic molecules as catalysts has gained increasing importance recently.
These substances, the so-called organocatalysts, present a lot of advantages, like being …
These substances, the so-called organocatalysts, present a lot of advantages, like being …
Catalyst‐Controlled Switch in Chemo‐and Diastereoselectivities: Annulations of Morita–Baylis–Hillman Carbonates from Isatins
G Zhan, ML Shi, Q He, WJ Lin… - Angewandte Chemie …, 2016 - Wiley Online Library
Regulating both the chemo‐and diastereoselectivity, divergently, of a reaction is highly
attractive but extremely challenging. Presented herein is a catalyst‐controlled switch in the …
attractive but extremely challenging. Presented herein is a catalyst‐controlled switch in the …
Switchable divergent di-or tricarboxylation of allylic alcohols with CO2
B Yu, Y Liu, HZ Xiao, SR Zhang, CK Ran, L Song… - Chem, 2024 - cell.com
Carboxylation with CO 2 has become an appealing and sustainable strategy to synthesize
valuable carboxylic acids and derivatives. Although significant progress in mono …
valuable carboxylic acids and derivatives. Although significant progress in mono …
Asymmetric Synthesis of Spirobenzazepinones with Atroposelectivity and Spiro‐1, 2‐Diazepinones by NHC‐Catalyzed [3+ 4] Annulation Reactions
L Wang, S Li, M Blümel, AR Philipps… - Angewandte …, 2016 - Wiley Online Library
A strategy for the NHC‐catalyzed asymmetric synthesis of spirobenzazepinones, spiro‐1, 2‐
diazepinones, and spiro‐1, 2‐oxazepinones has been developed via [3+ 4]‐cycloaddition …
diazepinones, and spiro‐1, 2‐oxazepinones has been developed via [3+ 4]‐cycloaddition …