Somatostatin analogs are an invaluable therapeutic option in the diagnosis and treatment of
somatotropinomas, thyrotropinomas, and functioning and non-functioning …

Diabetic retinopathy is one of the most serious microvascular complications induced by
hyperglycemia via five major pathways, including polyol, hexosamine, protein kinase C, and …

Diabetic retinopathy (DR) and diabetic macular edema (DME) are leading causes of
blindness in the working-age population of most developed countries. The increasing …

The retina was first described by Herophilus of Chalcedon around 300 bc. It was named by
Rufos of Ephesus (c. 110 ad) and appeared to early anatomists as a surrounding net which …

ContextDiabetic retinopathy (DR) is the leading cause of blindness in the working-aged
population in the United States. There are many new interventions for DR, but evidence to …

Over 135 million individuals are af-flicted with diabetes across the world. In the US, diabetes
affects over 18.2 million people (or 6.3% of the total population) and 800,000 new cases of …

Diabetic retinopathy continues to be the leading cause of legal blindness among working-
age individuals. The earliest histological features of diabetic retinopathy include neuroretinal …

Somatostatin is an endogeneous cyclic tetradecapeptide hormone that exerts multiple
biological activities via five ubiquitously distributed receptor subtypes. Classified as a broad …

Easy observation of the fundus oculi makes retinopathy the most frequently reported chronic
complication of diabetes and, consequently, the one we know best in terms of epidemiology …

Retinal angiogenesis and choroidal angiogenesis are major causes of vision loss, and the
pathogenesis of this angiogenesis process is still uncertain. However, several key steps of …