Homocysteine (Hcy) metabolism is crucial for regulating methionine availability, protein
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …

Folate (vitamin B9) is found in some water-soluble foods or as a synthetic form of folic acid
and is involved in many essential biochemical processes. Dietary folate is converted into …

Pyoderma gangrenosum (PG), hidradenitis suppurativa (HS), and the associated
autoinflammatory syndromes, including pyogenic arthritis, pyoderma gangrenosum, and …

Background Despite conflicting results, considerable evidence suggests the association
between single nucleotide polymorphisms in MTHFR, XRCC1 and OGG1 genes and, risk of …

Objective This study aimed to identify risk factors for NSCLP by analyzing polymorphisms in
IRF6 rs2013162 and MTHFR A1298C rs1801131 in the Deutero Malay Population in …

Background Presently incurable, metastatic breast cancer is estimated to occur in as many
as 30% of those diagnosed with early-stage breast cancer. Timely and accurate …

Lynch syndrome (LS) is characterised by an increased risk of developing colorectal cancer
(CRC) and other extracolonic epithelial cancers. It is caused by pathogenic germline …

Methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in regulating one-carbon
metabolism. Polymorphisms within the MTHFR gene have been found to increase the risk of …

Common variants of genes involved in DNA damage correction [tumor protein p53 (TP53),
murine double 2 homolog oncoprotein (MDM2) and ataxia‑telengiectasia mutated (ATM)] …

Background The detection and analysis of methylene tetrahydrofolate reductase (MTHFR)
C677T single nucleotide polymorphism (SNP) from blood samples is time-consuming and …