The long delay before genomic technologies become available in low-and middle-income
countries is a concern from both scientific and ethical standpoints. Polygenic risk scores …

Obesity rates are increasing almost everywhere in the world, although the pace and timing
for this increase differ when populations from developed and developing countries are …

Objective To introduce MexOMICS, a Mexican Consortium focused on establishing
electronic databases to collect, cross-reference, and share health-related and omics data on …

Chronic liver disease is a global health issue. Patients with chronic liver disease require a
fresh approach that focuses on the genetic and environmental factors that contribute to …

Linear growth during three distinct stages of life determines attained stature in adulthood:
namely, in utero, early postnatal life, and puberty and the adolescent period. Individual host …

Advances in precision medicine depend on the quantity and quality of available genomic
information. Various articles alert about the current disparities between the world's regions …

SNP heritability hsnp 2 is defined as the proportion of phenotypic variance explained by
genotyped SNPs and is believed to be a lower bound of heritability (h 2), being equal to it if …

Early-onset systemic lupus erythematosus presents with a more severe disease and is
associated with a greater genetic burden, especially in patients from Black, Asian or …

Diversifying genotype–phenotype databases is essential to understanding complex trait and
disease etiology across different environments and genetic ancestries. The rise of biobanks …

Deep learning models for predicting variant pathogenicity have not been thoroughly
evaluated on real-world clinical phenotypes. Here, we apply state-of-the-art pathogenicity …