Mitochondrial production of superoxide and hydrogen peroxide is potentially important in
cell signaling and disease. Eleven distinct mitochondrial sites that differ markedly in capacity …

Reactive oxygen species (ROS) including superoxide anion and hydrogen peroxide (H 2 O
2) are thought to be byproducts of aerobic respiration with damaging effects on DNA …

At high concentrations, free radicals and radical-derived, nonradical reactive species are
hazardous for living organisms and damage all major cellular constituents. At moderate …

Mitochondrial superoxide production is an important source of reactive oxygen species in
cells, and may cause or contribute to ageing and the diseases of ageing. Seven major sites …

The mitochondrial respiratory chain is a major source of reactive oxygen species (ROS) in
eukaryotic cells. Mitochondrial ROS production associated with a dysfunction of respiratory …

This review focuses on key components of respiratory and photosynthetic energy-
transduction systems: the cytochrome bc 1 and b 6 f (Cyt bc 1/b 6 f) membranous …

Oxidative stress is considered a major contributor to etiology of both “normal” senescence
and severe pathologies with serious public health implications. Mitochondria generate …

Ubiquinone (UQ; also known as coenzyme Q; CoQ) is a mobile component of the
mitochondrial electron transport chain, where it acts as a pro-oxidant in its ubisemiquinone …

Mitochondria play a central role in the survival and death of neurons. The detailed
bioenergetic mechanisms by which isolated mitochondria generate ATP, sequester Ca2+ …

Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …