Osteoporosis (OP) is a systemic bone disease characterized by decreased bone strength,
microarchitectural changes in bone tissues, and increased risk of fracture. Its occurrence is …

The inflammatory response is a complex regulated effector mechanism of the innate immune
system that is initiated after tissue injury or infection. The NLRP3 inflammasome is an …

Inflammatory reactions induce changes in the neuromuscular system. The mechanisms
underlying this link are unclear. Besides cytokines and reactive oxygen species (ROS) …

25-hydroxycholesterol (25-HC) is an oxysterol synthesized from cholesterol by cholesterol-
25-hydroxylase during cholesterol metabolism. The aim of this study was to verify whether …

Abstract Cholesterol‐25‐hydroxylase (CH25H) has been identified as an interferon‐
stimulated gene (ISG) in mammals that exerts its antiviral effects by catalyzing the …

Oxysterols, oxidized derivatives of cholesterol, act in breast cancer (BC) as selective
estrogen receptor modulators and affect cholesterol homeostasis, drug transport, nuclear …

Hepatic ischemia reperfusion (I/R) injury remains a major obstacle in liver transplantation,
however an effective treatment to mitigate this injury is lacking. 25-Hydroxycholesterol …

Avian reovirus (ARV) causing viral arthritis/tenosynovitis and viral enteritis in domestic fowl
has significantly threatened on the poultry industry worldwide. ARV is a non-enveloped …

Viruses have evolved complex and dynamic interactions with their host cells to enable viral
replication. In recent years, insights have been gained into the increasingly important role of …

Upgradable renewable crude oil produced from the hydrothermal liquefaction (HTL) of
municipal wastewater sludge (biosolids) has the potential to be a sustainable feedstock to …