Prognostic factors in skull base chordoma: a systematic literature review and meta-analysis

MX Zou, GH Lv, QS Zhang, SF Wang, J Li, XB Wang - World Neurosurgery, 2018 - Elsevier
Objective Currently, there are a lack of reviews assessing the complete range of prognostic
factors in skull base chordoma (SBC). This study aimed to systematically review the …

Clinical experience of intracranial chordoma–a systematic review and meta-analysis of the literature

P Leah, A Dower, C Vescovi, M Mulcahy… - Journal of Clinical …, 2018 - Elsevier
Chordomas are rare neoplasms of the axial skeleton, with a predilection for the clival region.
The lack of data about intracranial chordomas has led to inconsistent reporting of their …

Prognostic factors and survival outcome in patients with chordoma in the United States: a population-based analysis

IJ Lee, RJ Lee, DK Fahim - World neurosurgery, 2017 - Elsevier
Objective To evaluate prognostic factors of patients with chordoma through a population-
based analysis. Methods Surveillance, Epidemiology, and End Results (SEER) database …

[HTML][HTML] Expression of programmed death-1 ligand (PD-L1) in tumor-infiltrating lymphocytes is associated with favorable spinal chordoma prognosis

MX Zou, AB Peng, GH Lv, XB Wang, J Li… - American journal of …, 2016 - ncbi.nlm.nih.gov
Aberrant expression of programmed death-1 (PD-1) receptor/PD-1 ligand (PD-L1) proteins
alters human immunoresponse and promotes tumor development and progression. We …

Development of machine learning algorithms for prediction of 5-year spinal chordoma survival

AV Karhade, Q Thio, P Ogink, J Kim… - World neurosurgery, 2018 - Elsevier
Background Chordomas are locally invasive slow-growing tumors that are difficult to study
because of the rarity of the tumors and the lack of significant volumes of patients with …

Radiotherapy after gross-total resection and subtotal resection of spinal chordoma: a SEER database analysis of overall survival outcomes

J Gendreau, CC Kuo, Y Mehkri, S Chakravarti… - … of Neurosurgery: Spine, 2023 - thejns.org
OBJECTIVE Chordomas are most frequently found in the sacrum, vertebral column, and
skull base. Achieving gross-total resection (GTR) has been shown to optimize overall …

Cervical chordomas: multicenter case series and meta-analysis

OO Akinduro, DP Garcia, RA Domingo… - Journal of neuro …, 2021 - Springer
Background En bloc spondylectomy is the gold standard for surgical resection of sacral
chordomas (CHO), but the effect of extent of resection on recurrence and survival in patients …

Association between immunohistochemical markers and tumor progression following resection of spinal chordomas: a multicenter study: Presented at the 2023 AANS …

AK Ghaith, OO Akinduro, C Perez-Vega… - … of Neurosurgery: Spine, 2023 - thejns.org
OBJECTIVE Chordomas are slow-growing tumors derived from notochord remnants.
Despite margin-negative excision and postoperative radiation therapy, spinal chordomas …

[HTML][HTML] Lymphocyte-related inflammation and immune-based scores predict prognosis of chordoma patients after radical resection

W Hu, J Yu, Y Huang, F Hu, X Zhang, Y Wang - Translational oncology, 2018 - Elsevier
The inflammatory microenvironment plays a critical role in the development and progression
of malignancies. In the present study, we aimed to evaluate the prognostic value of …

Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth

S Khan, JA Zuccato, V Ignatchenko, O Singh… - Acta Neuropathologica …, 2024 - Springer
Chordomas are clinically aggressive tumors with a high rate of disease progression despite
maximal therapy. Given the limited therapeutic options available, there remains an urgent …