Nitric oxide signaling and the regulation of myocardial function

MT Ziolo, MJ Kohr, H Wang - Journal of molecular and cellular cardiology, 2008 - Elsevier
Nitric oxide, which is produced endogenously within cardiac myocytes by three distinct
isoforms of nitric oxide synthase, is a key regulator of myocardial function. This review will …

[PDF][PDF] Pathophysiology of myocardial ischemia reperfusion injury: a review

H Parlakpinar, MH Orum, M Sagir - Medicine Science, 2013 - dergipark.org.tr
Cardiovascular events are one of the leading causes of death in the world. Thrombolysis,
percutaneous transluminal coronary angioplasty, and coronary bypass surgery are the …

Extraction, chemical analysis of Angelica sinensis polysaccharides and antioxidant activity of the polysaccharides in ischemia–reperfusion rats

S Zhang, B He, J Ge, H Li, X Luo, H Zhang, Y Li… - International Journal of …, 2010 - Elsevier
Angelica sinensis polysaccharides were analyzed using high performance liquid
chromatography (HPLC) and Fourier Transform Infrared (FT-IR). The major sugar of the …

Long-term inorganic nitrate administration protects against myocardial ischemia-reperfusion injury in female rats

Y Yassaghi, S Jeddi, N Yousefzadeh, K Kashfi… - BMC Cardiovascular …, 2023 - Springer
Background The favorable effects of nitrate against myocardial ischemia-reperfusion injury
(MIRI) have primarily focused on male rats and in short term. Here we determine the impact …

Beneficial effects of apricot-feeding on myocardial ischemia-reperfusion injury in rats

H Parlakpinar, E Olmez, A Acet, F Ozturk… - Food and chemical …, 2009 - Elsevier
The present study was undertaken to evaluate the cardio-protective potential of apricot-
feeding in the ischemia-reperfusion (I/R) model of rats in vivo. Rats were divided into three …

Aminoguanidine prevents the oxidative stress, inhibiting elements of inflammation, endothelial activation, mesenchymal markers, and confers a renoprotective effect in …

C Pasten, M Lozano, J Rocco, F Carrión, C Alvarado… - Antioxidants, 2021 - mdpi.com
Oxidative stress produces macromolecules dysfunction and cellular damage. Renal
ischemia-reperfusion injury (IRI) induces oxidative stress, inflammation, epithelium and …

Inhibition of NADPH oxidase by apocynin promotes myocardial antioxidant response and prevents isoproterenol-induced myocardial oxidative stress in rats

LH Tanriverdi, H Parlakpinar, O Ozhan… - Free Radical …, 2017 - Taylor & Francis
Preventive and/or therapeutic interventions for ischemic heart disease have gained
considerable attention worldwide. We investigated the mechanism (s) underlying …

Selective endothelin a (ETA) receptor antagonist (BQ-123) reduces both myocardial infarct size and oxidant injury

R Ozdemir, H Parlakpinar, A Polat, C Colak, N Ermis… - Toxicology, 2006 - Elsevier
OBJECTIVE: Endothelins (ET) can be considered stress-responsive regulators working in
paracrine and autocrine fashion. It has been suggested that elevated levels of ET may be …

Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia–Reperfusion Injury in Male Wistar Rats: Modulation of RKIP, NF-κB …

S Jeddi, S Gheibi, K Kashfi, M Carlström… - International journal of …, 2020 - mdpi.com
Decreased circulating levels of hydrogen sulfide (H2S) are associated with higher mortality
following myocardial ischemia. This study aimed at determining the long-term dose …

Beneficial effects of aminoguanidine on skin flap survival in diabetic rats

A Ozturk, C Fırat, H Parlakpınar… - Journal of Diabetes …, 2012 - Wiley Online Library
Random flaps in DM patients have poor reliability for wound coverage, and flap loss remains
a complex challenge. The protective effects of aminoguanidine (AG) administration on the …