[HTML][HTML] Gout: An old disease in new perspective–A review

G Ragab, M Elshahaly, T Bardin - Journal of advanced research, 2017 - Elsevier
Gout is a picturesque presentation of uric acid disturbance. It is the most well understood
and described type of arthritis. Its epidemiology is studied. New insights into the …

Elevated serum uric acid levels in metabolic syndrome: an active component or an innocent bystander?

SG Tsouli, EN Liberopoulos, DP Mikhailidis… - Metabolism, 2006 - Elsevier
Elevated serum uric acid (SUA) levels are commonly seen in patients with the metabolic
syndrome (MetS). Several mechanisms, both direct and indirect, connect the increased SUA …

Effects of sodium‐glucose co‐transporter 2 (SGLT2) inhibitors on serum uric acid level: a meta‐analysis of randomized controlled trials

Y Zhao, L Xu, D Tian, P Xia, H Zheng… - Diabetes, Obesity …, 2018 - Wiley Online Library
The aim of this study was to describe the effects of sodium‐glucose co‐transporter 2
(SGLT2) inhibitors on serum uric acid (SUA) in patients with type 2 diabetes mellitus (T2DM) …

A causal role for uric acid in fructose-induced metabolic syndrome

T Nakagawa, H Hu, S Zharikov… - American Journal …, 2006 - journals.physiology.org
The worldwide epidemic of metabolic syndrome correlates with an elevation in serum uric
acid as well as a marked increase in total fructose intake (in the form of table sugar and high …

Metabolic syndrome and self-reported history of kidney stones: the National Health and Nutrition Examination Survey (NHANES III) 1988-1994

B West, A Luke, RA Durazo-Arvizu, G Cao… - American Journal of …, 2008 - Elsevier
BACKGROUND: Metabolic syndrome affects approximately 25% of the American
population. Components of metabolic syndrome, such as obesity, hypertension, and …

Expert consensus for the diagnosis and treatment of patient with hyperuricemia and high cardiovascular risk

C Borghi, A Tykarski, K Widecka, KJ Filipiak… - Cardiology …, 2018 - journals.viamedica.pl
The definition of hyperuricemia (HU) varies widely in different studies, which makes the
epidemiological reports somewhat inconsistent. HU remains the culprit of the pathogenesis …

Serum uric acid is an independent predictor of all‐cause mortality in patients at high risk of cardiovascular disease: a preventive cardiology information system …

AG Ioachimescu, DM Brennan, BM Hoar… - … : Official Journal of …, 2008 - Wiley Online Library
Objective Uric acid is a product of the activity of xanthine oxidase, an enzyme linked to
oxidative stress, endothelial dysfunction, and heart failure. It is unclear whether adding uric …

Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit

F McTaggart, P Jones - Cardiovascular Drugs and therapy, 2008 - Springer
Purpose The objective was to systematically review clinical trial data on the effects of statins
on high-density lipoproteins (HDL) and to examine the possibility that this provides …

Relationship between serum uric acid concentration, metabolic syndrome and carotid atherosclerosis

R Kawamoto, H Tomita, Y Oka, N Ohtsuka - Internal Medicine, 2006 - jstage.jst.go.jp
Objective: Carotid intima-media thickness (IMT) is a useful surrogate marker of
cardiovascular disease. Associations between hyperuricemia, metabolic syndrome and …

Pleiotropic effects of statins-clinical evidence

VG Athyros, AI Kakafika, K Tziomalos… - Current …, 2009 - ingentaconnect.com
The present review considers the potential pleiotropic effects of statins and the evidence
indicative of the “real world” benefit from these effects in patients with cardiovascular …