Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

The 70-kDa heat shock proteins (HSP70s) are abundantly present in cancer, providing
malignant cells selective advantage by suppressing multiple apoptotic pathways, regulating …

Heat shock proteins 70 (HSP70s) are steadily gaining more attention in the field of plant
biotic interactions. Though their regulation and activity in plants are much less well …

Stem cells have emerged as a key element of regenerative medicine therapies due to their
inherent ability to differentiate into a variety of cell phenotypes, thereby providing numerous …

Cells respond to protein-damaging (proteotoxic) stress by activation of the Heat Shock
Response (HSR). The HSR provides cells with an enhanced ability to endure proteotoxic …

Heat shock proteins (HSPs) are a large family of molecular chaperones aberrantly
expressed in cancer. The expression of HSPs in tumor cells has been shown to be …

Extracellular vesicles (EVs) released by parasites have important roles in establishing and
maintaining infection. Analysis of the soluble and vesicular secretions of adult Fasciola …

The paradoxical appearance of aggregated α-synuclein (αsyn) in naive transplanted
embryonic stem cells in Parkinson's disease (PD) brains has recently been reported …

Stress or heat shock proteins (HSPs) 70 and 90 are powerful chaperones whose expression
is induced in response to a wide variety of physiological and environmental insults. These …

Amyloid is aggregated protein in the form of insoluble fibrils. Amyloid deposition in human
tissue—amyloidosis—is associated with a number of diseases including all common …