Hybrid nanosystems for biomedical applications

J Seaberg, H Montazerian, MN Hossen… - ACS …, 2021 - ACS Publications
Inorganic/organic hybrid nanosystems have been increasingly developed for their versatility
and efficacy at overcoming obstacles not readily surmounted by nonhybridized counterparts …

Challenges identifying efficacious miRNA therapeutics for cancer

M Segal, FJ Slack - Expert opinion on drug discovery, 2020 - Taylor & Francis
MicroRNAs are a class of small non-coding RNAs (22-23 nucleotides), which regulate gene
expression at the posttranscriptional level and play key roles in tumorigenesis and other …

Multifunctional stimuli-responsive niosomal nanoparticles for co-delivery and co-administration of gene and bioactive compound: In vitro and in vivo studies

NA Abtahi, SM Naghib, SJ Ghalekohneh… - Chemical Engineering …, 2022 - Elsevier
This study aims to optimize niosomes for carrying and delivering the anticancer agents and
genes, simultaneously. We synthesized new cationic niosomal formulations containing …

Effects of zeolite as a drug delivery system on cancer therapy: a systematic review

J Hao, I Stavljenić Milašin, Z Batu Eken… - Molecules, 2021 - mdpi.com
Zeolites and zeolitic imidazolate frameworks (ZIFs) are widely studied as drug carrying
nanoplatforms to enhance the specificity and efficacy of traditional anticancer drugs. At …

Zeolites for theranostic applications

MK Yazdi, P Zarrintaj, H Hosseiniamoli… - Journal of Materials …, 2020 - pubs.rsc.org
Theranostic platforms bring about a revolution in disease management. During recent years,
theranostic nanoparticles have been utilized for imaging and therapy simultaneously …

Composition, preparation methods, and applications of nanoniosomes as codelivery systems: a review of emerging therapies with emphasis on cancer

M Roostaee, A Derakhshani, H Mirhosseini… - Nanoscale, 2024 - pubs.rsc.org
Nanoniosome-based drug codelivery systems have become popular therapeutic
instruments, demonstrating tremendous promise in cancer therapy, infection treatment, and …

[HTML][HTML] Metabolic disorders affecting the liver and heart: Therapeutic efficacy of miRNA-based therapies?

L La Sala, V Carlini, C Conte… - Pharmacological …, 2024 - Elsevier
Liver and heart disease are major causes of death worldwide. It is known that metabolic
alteration causing type 2 diabetes (T2D) and Nonalcoholic fatty liver (NAFLD) coupled with a …

Targeted delivery of miR-218 via decorated hyperbranched polyamidoamine for liver cancer regression

AM Elfiky, RH Mohamed, FEZ Abd EL-Hakam… - International Journal of …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is one of most common causes of cancer death worldwide.
MicroRNA (miRNA) replacement gene therapy is a novel approach for HCC management …

Cell-free biological approach for corneal stromal wound healing

V Jhanji, I Billig, GHF Yam - Frontiers in Pharmacology, 2021 - frontiersin.org
Corneal opacification is the fourth most common cause of blindness globally behind
cataracts, glaucoma, and age-related macular degeneration. The standard treatment of …

[HTML][HTML] Diverse functions of SOX9 in liver development and homeostasis and hepatobiliary diseases

T Shang, T Jiang, X Cui, Y Pan, X Feng, L Dong… - Genes & …, 2024 - Elsevier
The liver is the central organ for digestion and detoxification and has unique metabolic and
regenerative capacities. The hepatobiliary system originates from the foregut endoderm, in …