[HTML][HTML] Microglia in Alzheimer's disease: a target for therapeutic intervention
G Zhang, Z Wang, H Hu, M Zhao, L Sun - Frontiers in Cellular …, 2021 - frontiersin.org
Alzheimer's disease (AD) is one of the most common types of age-related dementia
worldwide. In addition to extracellular amyloid plaques and intracellular neurofibrillary …
worldwide. In addition to extracellular amyloid plaques and intracellular neurofibrillary …
[HTML][HTML] Fat therapeutics: the clinical capacity of adipose-derived stem cells and exosomes for human disease and tissue regeneration
L Shukla, Y Yuan, R Shayan, DW Greening… - Frontiers in …, 2020 - frontiersin.org
Fat grafting is a well-established surgical technique used in plastic surgery to restore
deficient tissue, and more recently, for its putative regenerative properties. Despite more …
deficient tissue, and more recently, for its putative regenerative properties. Despite more …
[HTML][HTML] Bone marrow-derived mesenchymal stem cells improve cognitive impairment in an Alzheimer's disease model by increasing the expression of microRNA …
M Nakano, K Kubota, E Kobayashi, TS Chikenji… - Scientific reports, 2020 - nature.com
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β and tau. We
previously reported that administration of bone marrow mesenchymal stem cells (BM-MSCs) …
previously reported that administration of bone marrow mesenchymal stem cells (BM-MSCs) …
Exosomes derived from hypoxia‐preconditioned mesenchymal stromal cells ameliorate cognitive decline by rescuing synaptic dysfunction and regulating …
GH Cui, J Wu, FF Mou, WH Xie, FB Wang… - The FASEB …, 2018 - Wiley Online Library
Administration of exosomes derived from mesenchymal stromal cells (MSCs) could improve
some neurologic conditions by transferring functional biomolecules to recipient cells …
some neurologic conditions by transferring functional biomolecules to recipient cells …
[HTML][HTML] Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
Background Inflammation is a key contributor to central nervous system (CNS) injury such as
stroke, and is a major target for therapeutic intervention. Effective treatments for CNS injuries …
stroke, and is a major target for therapeutic intervention. Effective treatments for CNS injuries …
Electrical stimulation promotes stem cell neural differentiation in tissue engineering
H Cheng, Y Huang, H Yue, Y Fan - Stem cells international, 2021 - Wiley Online Library
Nerve injuries and neurodegenerative disorders remain serious challenges, owing to the
poor treatment outcomes of in situ neural stem cell regeneration. The most promising …
poor treatment outcomes of in situ neural stem cell regeneration. The most promising …
Functional role of mesenchymal stem cells in the treatment of chronic neurodegenerative diseases
D Lo Furno, G Mannino… - Journal of cellular …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) can differentiate into not only cells of mesodermal
lineages, but also into endodermal and ectodermal derived elements, including neurons …
lineages, but also into endodermal and ectodermal derived elements, including neurons …
Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice
C Wang, X Zhang, Z Teng, T Zhang, Y Li - European journal of …, 2014 - Elsevier
Autophagy is a lysosomal degradation pathway, which is essential for cell survival,
proliferation, differentiation and homeostasis. It is well known that beta-amyloid (Aβ) …
proliferation, differentiation and homeostasis. It is well known that beta-amyloid (Aβ) …
NLRP3 inflammasome in ischemic stroke: as possible therapeutic target
M Alishahi, M Farzaneh… - … Journal of Stroke, 2019 - journals.sagepub.com
Inflammation is a devastating pathophysiological process during stroke, a devastating
disease that is the second most common cause of death worldwide. Activation of the NOD …
disease that is the second most common cause of death worldwide. Activation of the NOD …
[HTML][HTML] Adipose tissue stem cells for therapy: an update on the progress of isolation, culture, storage, and clinical application
DT Chu, T Nguyen Thi Phuong, NLB Tien… - Journal of Clinical …, 2019 - mdpi.com
Adipose tissue stem cells (ASCs), known as multipotent stem cells, are most commonly used
in the clinical applications in recent years. Adipose tissues (AT) have the advantage in the …
in the clinical applications in recent years. Adipose tissues (AT) have the advantage in the …