[HTML][HTML] Brain-derived neurotrophic factor signaling in depression and antidepressant action

E Castrén, LM Monteggia - Biological psychiatry, 2021 - Elsevier
Neurotrophic factors, particularly BDNF (brain-derived neurotrophic factor), have been
associated with depression and antidepressant drug action. A variety of preclinical and …

The effects of acute exercise on mood, cognition, neurophysiology, and neurochemical pathways: a review

JC Basso, WA Suzuki - Brain Plasticity, 2017 - content.iospress.com
A significant body of work has investigated the effects of acute exercise, defined as a single
bout of physical activity, on mood and cognitive functions in humans. Several excellent …

Brain‐derived neurotrophic factor, depression, and physical activity: making the neuroplastic connection

C Phillips - Neural plasticity, 2017 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is a neurotrophin that is vital to the survival,
growth, and maintenance of neurons in key brain circuits involved in emotional and …

Bridging animal and human models of exercise-induced brain plasticity

MW Voss, C Vivar, AF Kramer, H van Praag - Trends in cognitive sciences, 2013 - cell.com
Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

B Lu, G Nagappan, X Guan, PJ Nathan… - Nature Reviews …, 2013 - nature.com
Increasing evidence suggests that synaptic dysfunction is a key pathophysiological hallmark
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …

Neuroplasticity—exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects

K Knaepen, M Goekint, EM Heyman, R Meeusen - Sports medicine, 2010 - Springer
Exercise is known to induce a cascade of molecular and cellular processes that support
brain plasticity. Brain-derived neurotrophic factor (BDNF) is an essential neurotrophin that is …

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

AH Nagahara, MH Tuszynski - Nature reviews Drug discovery, 2011 - nature.com
The growth factor brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …

Neurotrophin signalling: novel insights into mechanisms and pathophysiology

M Mitre, A Mariga, MV Chao - Clinical science, 2017 - portlandpress.com
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are prominent regulators
of neuronal survival, growth and differentiation during development. While trophic factors are …

Promoting neuroplasticity for motor rehabilitation after stroke: considering the effects of aerobic exercise and genetic variation on brain-derived neurotrophic factor

CS Mang, KL Campbell, CJD Ross, LA Boyd - Physical therapy, 2013 - academic.oup.com
Recovery of motor function after stroke involves relearning motor skills and is mediated by
neuroplasticity. Recent research has focused on developing rehabilitation strategies that …

Brain-derived neurotrophic factor and major depressive disorder: evidence from meta-analyses

T Kishi, R Yoshimura, T Ikuta, N Iwata - Frontiers in psychiatry, 2018 - frontiersin.org
Accumulating evidence suggests that brain-derived neurotrophic factor (BDNF) is
associated with the pathophysiology of major depressive disorder (MDD). In this mini review …