Cerebrovascular reactivity (CVR) magnetic resonance imaging (MRI) probes cerebral
haemodynamic changes in response to a vasodilatory stimulus. CVR closely relates to the …

The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

Objective To investigate cerebrovascular reactivity (CVR), blood flow, vascular and CSF
pulsatility, and their independent relationship with cerebral small vessel disease (SVD) …

Vascular smooth muscle cells (VSMCs) are the key moderators of cerebrovascular dynamics
in response to the brain's oxygen and nutrient demands. Crucially, VSMCs may provide a …

Background: The incidence of dementia is projected to rise over the coming decades, but
with no sensitive diagnostic tests available. Vascular pathology precedes the deposition of …

Functional brain network analysis has become one principled way of revealing informative
organization architectures in healthy brains, and providing sensitive biomarkers for …

We define cerebral vascular reactivity (CVR) as the ratio of the change in blood oxygen level-
dependent (BOLD) magnetic resonance imaging (MRI) signal (S) to an increase in blood …

Background and Objectives Reduced cerebrovascular reactivity is proposed to be a feature
of cerebral amyloid angiopathy (CAA) but has not been measured directly. Employing a …

Temporal synchronization-based functional connectivity (FC) has long been used by the
neuroscience community. However, topographical FC information may provide additional …

Brain aging and associated neurodegeneration constitute a major societal challenge as well
as one for the neuroimaging community. A full understanding of the physiological …