Engineering therapeutical extracellular vesicles for clinical translation
Cell-based therapies are revolutionizing medicine by replacing or modifying dysfunctional
cells with healthy cells or engineered derivatives, offering disease reversal and cure. One …
cells with healthy cells or engineered derivatives, offering disease reversal and cure. One …
[HTML][HTML] Microfluidics for personalized drug delivery
This review highlights the transformative impact of microfluidic technology on personalized
drug delivery. Microfluidics addresses issues in traditional drug synthesis, providing precise …
drug delivery. Microfluidics addresses issues in traditional drug synthesis, providing precise …
Dacarbazine-primed carbon quantum dots coated with breast cancer cell-derived exosomes for improved breast cancer therapy
P Tiwari, RP Shukla, K Yadav, N Singh… - Journal of Controlled …, 2024 - Elsevier
Imprecise targeting of chemotherapeutic drugs often leads to severe toxicity during breast
cancer therapy. To address this issue, we have devised a strategy to load dacarbazine (DC) …
cancer therapy. To address this issue, we have devised a strategy to load dacarbazine (DC) …
A fractional-order model for optimizing combination therapy in heterogeneous lung cancer: integrating immunotherapy and targeted therapy to minimize side effects
This research presents a novel approach to address the complexities of heterogeneous lung
cancer dynamics through the development of a Fractional-Order Model. Focusing on the …
cancer dynamics through the development of a Fractional-Order Model. Focusing on the …
Surface-modified lyotropic crystalline nanoconstructs bearing doxorubicin and buparvaquone target sigma receptors through pH-sensitive charge conversion to …
In the current study, we aimed to develop lyotropic crystalline nanoconstructs (LCNs) based
on poly (l-glutamic acid)(PLG) with a two-tier strategy. The first objective was to confer pH …
on poly (l-glutamic acid)(PLG) with a two-tier strategy. The first objective was to confer pH …
Exploring nanocarriers as innovative materials for advanced drug delivery strategies in onco-immunotherapies
P Tiwari, RP Shukla, K Yadav, D Panwar… - Journal of Molecular …, 2024 - Elsevier
In recent years, Onco-immunotherapies (OIMTs) have been shown to be a potential therapy
option for cancer. Several immunotherapies have received regulatory approval, while many …
option for cancer. Several immunotherapies have received regulatory approval, while many …
Alendronate-functionalized porous nano-crystalsomes mitigate osteolysis and consequent inhibition of tumor growth in a tibia-induced metastasis model
Bone is one of the most prevalent sites of metastases in various epithelial malignancies,
including breast cancer and this metastasis to bone often leads to severe skeletal …
including breast cancer and this metastasis to bone often leads to severe skeletal …
[HTML][HTML] A complex molecular landscape to drug delivery concept for achieving precise therapy in psoriasis
K Yadav, KK Sahu, R Yadav, W Raza, S Minz… - Medicine in Drug …, 2024 - Elsevier
Psoriasis is a chronic autoimmune disorder that has a major effect on the quality of life for
millions of people throughout the world. The pathogenesis of psoriasis has revealed intricate …
millions of people throughout the world. The pathogenesis of psoriasis has revealed intricate …
Recent updates on ocular disease management with ophthalmic ointments
Ophthalmic diseases can result in permanent vision loss and blindness. Convenient topical
and systemic treatments are preferred to address these sight-threatening conditions …
and systemic treatments are preferred to address these sight-threatening conditions …
Extracellular vesicles-powered immunotherapy: Unleashing the potential for safer and more effective cancer treatment
Cancer treatment has seen significant advancements with the introduction of Onco-
immunotherapies (OIMTs). Although some of these therapies have received approval for …
immunotherapies (OIMTs). Although some of these therapies have received approval for …