Engineering the multiscale complexity of vascular networks

C O'Connor, E Brady, Y Zheng, E Moore… - Nature Reviews …, 2022 - nature.com
The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

Advances in organ-on-a-chip engineering

B Zhang, A Korolj, BFL Lai, M Radisic - Nature Reviews Materials, 2018 - nature.com
Predicting the effects of drugs before human clinical trials is at the heart of drug screening
and discovery processes. The cost of drug discovery is steadily increasing owing to the …

Biofabrication strategies for 3D in vitro models and regenerative medicine

L Moroni, JA Burdick, C Highley, SJ Lee… - Nature Reviews …, 2018 - nature.com
Organs are complex systems composed of different cells, proteins and signalling molecules
that are arranged in a highly ordered structure to orchestrate a myriad of functions in our …

Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Progress of microfluidic hydrogel‐based scaffolds and organ‐on‐chips for the cartilage tissue engineering

H Tolabi, N Davari, M Khajehmohammadi… - Advanced …, 2023 - Wiley Online Library
Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

[HTML][HTML] Emergence of microfluidics for next generation biomedical devices

S Preetam, BK Nahak, S Patra, DC Toncu… - … and Bioelectronics: X, 2022 - Elsevier
The attention in lab-on-a-chip devices with their potent application in medical engineering
has prolonged swiftly over the last ten years. Travelling through the technology …

Direct 3D bioprinting of perfusable vascular constructs using a blend bioink

W Jia, PS Gungor-Ozkerim, YS Zhang, K Yue, K Zhu… - Biomaterials, 2016 - Elsevier
Despite the significant technological advancement in tissue engineering, challenges still
exist towards the development of complex and fully functional tissue constructs that mimic …

Manufacturing of hydrogel biomaterials with controlled mechanical properties for tissue engineering applications

A Vedadghavami, F Minooei, MH Mohammadi… - Acta biomaterialia, 2017 - Elsevier
Hydrogels have been recognized as crucial biomaterials in the field of tissue engineering,
regenerative medicine, and drug delivery applications due to their specific characteristics …

Direct 3D Printing of Shear-Thinning Hydrogels into Self-Healing Hydrogels.

CB Highley, CB Rodell, JA Burdick - Advanced materials (Deerfield …, 2015 - europepmc.org
Supramolecular hydrogels are used in the 3D printing of high-resolution, multi-material
structures. The non-covalent bonds allow the extrusion of the inks into support gels to …