Natural Products That Target the Arginase in Leishmania Parasites Hold Therapeutic Promise
NS Carter, BD Stamper, F Elbarbry, V Nguyen, S Lopez… - Microorganisms, 2021 - mdpi.com
Parasites of the genus Leishmania cause a variety of devastating and often fatal diseases in
humans worldwide. Because a vaccine is not available and the currently small number of …
humans worldwide. Because a vaccine is not available and the currently small number of …
In vitro and in vivo therapeutic potentials of 6-gingerol in combination with amphotericin B for treatment of Leishmania major infection: Powerful synergistic and …
The ongoing conventional drugs for leishmaniasis treatment are insufficient. The present
study aimed to assess 6-gingerol alone and in combination with amphotericin B on …
study aimed to assess 6-gingerol alone and in combination with amphotericin B on …
Assessment of the antileishmanial activity of diallyl sulfide combined with meglumine antimoniate on Leishmania major: Molecular docking, in vitro, and animal …
Currently, no safe vaccine against leishmaniasis is available. So far, different control
strategies against numerous reservoir hosts and biological vectors have not been …
strategies against numerous reservoir hosts and biological vectors have not been …
Antileishmanial potentials of azacitidine and along with meglumine antimoniate on Leishmania major: In silico prediction and in vitro analysis
This study aimed to investigate the in vitro and in silico antileishmanial activity of azacitidine
(AZA) on Leishmania major promastigotes and amastigotes. The in silico method was used …
(AZA) on Leishmania major promastigotes and amastigotes. The in silico method was used …
HAS 1: A natural product from soil-isolated Streptomyces species with potent activity against cutaneous leishmaniasis caused by Leishmania tropica
Cutaneous Leishmaniasis (CL) is a neglected tropical disease, classified by the World
Health Organization (WHO) as one of the most unrestrained diseases. The Syrian war and …
Health Organization (WHO) as one of the most unrestrained diseases. The Syrian war and …
The potential effect of silver nanoparticles synthesized with Coffea arabica green seeds on Leishmania major proliferation, cytotoxicity activity, and cytokines …
F Sharifi, N Mohamadi, R Tavakoli Oliaee… - Journal of Parasitic …, 2023 - Springer
The goal of this study was to analyze the antileishmanial and antibacterial activity of Coffea
arabica green seed biosynthesize silver nanoparticles (C. arabica AgNPs), as well as …
arabica green seed biosynthesize silver nanoparticles (C. arabica AgNPs), as well as …
In silico and experimental potentials of 6-shogaol and meglumine antimoniate on Leishmania major: multiple synergistic combinations through modulation of …
Conventional therapeutic agents are no longer adequate against leishmaniasis. This
complex condition continues to have a high mortality rate and public health impact. The …
complex condition continues to have a high mortality rate and public health impact. The …
Leishmanicidal potentials of Gossypium hirsutum extract and its fractions on Leishmania major in a murine model: parasite burden, gene expression, and …
F Sharifi, F Sharififar, M Pournamdari… - Journal of Medical …, 2021 - microbiologyresearch.org
Introduction. Leishmaniasis is a neglected tropical and subtropical disease caused by over
20 protozoan species. Hypothesis. Treatment of this complex disease with traditional …
20 protozoan species. Hypothesis. Treatment of this complex disease with traditional …
[HTML][HTML] Anti-leishmanial activity of Avicennia marina (Avicenniaceae family) leaves hydroalcoholic extract and its possible cellular mechanisms
Natural products are the main source of potent antioxidants and anti-leishmanial agents.
This study was aimed to evaluate Avicennia marina (Avicenniaceae family) extract inhibitory …
This study was aimed to evaluate Avicennia marina (Avicenniaceae family) extract inhibitory …
In silico and in vitro potentials of crocin and amphotericin B on Leishmania major: Multiple synergistic mechanisms of actions
A significant barrier to optimal antileishmanial treatment is low efficacy and the emergence
of drug resistance. Multiple approaches were used to monitor and assess crocin (a central …
of drug resistance. Multiple approaches were used to monitor and assess crocin (a central …