Since our previous review, 1 there has been a tremendous development in the field of
carbazole alkaloids. New synthetic methodologies have been developed, existing …

Natural products and their derivatives play an important role in modern healthcare as
frontline treatments for many diseases and as inspiration for chemically synthesized …

Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

The indolocarbazoles are an important class of nitrogen heterocycles which has evolved
significantly in recent years, with numerous studies focusing on their diverse biological …

Microorganisms have become an increasingly important platform for the production of drugs,
chemicals, and biofuels from renewable resources. Advances in protein engineering …

Down syndrome (DS) is one of the leading causes of intellectual disability, and patients with
DS face various health issues, including learning and memory deficits, congenital heart …

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a member of an
evolutionarily conserved family of protein kinases that belongs to the CMGC group of …

Autoimmune deficiency and destruction in either β-cell mass or function can cause
insufficient insulin levels and, as a result, hyperglycemia and diabetes. Thus, promoting β …

With 24.3 million people affected in 2005 and an estimated rise to 42.3 million in 2020,
dementia is currently a leading unmet medical need and costly burden on public health …

DYRK1A (dual-specificity tyrosine-regulated kinase 1A) is a kinase with multiple implications
for embryonic development, especially in the nervous system where it regulates the balance …