Ligusticum chuanxiong Hort (known as Chuanxiong in China, CX) is one of the most widely
used and long-standing medicinal herbs in China. Tetramethylpyrazine (TMP) is an alkaloid …

Tetramethylpyrazine, a natural compound from Ligusticum wallichii (Chuan Xiong), has
been extensively used in China for cardiovascular and cerebrovascular diseases for about …

Ischemic stroke is a common disease with high mortality and morbidity worldwide. One of
the important pathophysiological effects of ischemic stroke is apoptosis. A neuroprotective …

Background Diabetic patients are highly vulnerable to hypoxic injury, which is associated
with hypoxia induced BNIP3 expression that subsequently activate apoptosis. Our previous …

Acute myocardial infarction (AMI) results from long-term diminished blood supply
diminishment (ischemia) to the heart, and the main reason for ischemia is hypoxia. BCL2 …

Background/Aims: Acute myocardial infarction (AMI) occurs when blood supply to the heart
is diminished (ischemia) for long time; ischemia is primarily caused due to hypoxia. The …

Periodontitis is a highly prevalent infectious disease, characterized by destruction of the
periodontium, and is the main cause of tooth loss. Periodontitis is initiated by periodontal …

Acute myocardial infarction (AMI) occurs when blood supply to the heart is diminished
(ischemia) for long time, and ischemia is primarily caused due to hypoxia. This study …

Retinal ischemia is a leading cause of irreversible blindness worldwide. Inner retinal
dysfunction including loss of retinal ganglion cells is encountered in a number of retinal …

The purpose of this study was to examine the possible mechanism underlying the protective
effect of tetramethylpyrazine (TMP) against disuse-induced muscle atrophy. Sprague …